Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Decoding center"”.
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Translational Control by the Ribosome-Associated Complex in the Unfolded Protein Response
… chain near the polypeptide exit tunnel and the decoding center on the 60S and 40S ribosomal subunits, respectively. Its unique position on the ribosome implies the coordinating role of de novo protein folding with translation. Deletion of RAC causes growth defects and sensitizes to osmotic, …
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Investigating the Molecular Mechanism of Ribosome Recycling
… additional interactions amikacin makes with the decoding center. The binding site in the large ribosomal subunit proximal to the 3’-end of tRNA in the peptidyl (P) site lays the groundwork for rational design of amikacin derivatives with improved antibacterial properties. Using time-resolved …
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Mechanisms and Evolution of Mitoribosomal Small Subunit Biogenesis
… folding and modification of key functional centers in the mitochondrial rRNA such as the decoding center. In parallel, we solved structures of three similar mitoribosomal small subunit assembly intermediates from the yeast S. cerevisiae. By comparing these assembly pathways, we can connect …
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Computational Techniques Applied to RNA Structures and Bacterial Genomes
… between the PTC region of the ribosome and the decoding center on the small ribosomal subunit. This is facilitated by changes in the orientation of 5S rRNA. The canonical 5S rRNA secondary structure includes 30 non-standard base-base interactions. The initial expectation was that these …
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Επίδραση ορισμένων ριβοσωματικών συστατικών επί της πρωτεϊνοσύνθεσης και επί εξωριβοσωματικών λειτουργιών του ευκαρυωτικού κυττάρου
Ο σκοπός της παρούσας διατριβής εστιάζεται στη διερεύνηση της λειτουργίας και της δομής του ευκαρυωτικού ριβοσώματος. Συγκεκριμένα, ερευνά την επίδραση ορισμένων συστατικών του ριβοσωματικού RNA (rRNA) της μεγάλης και της μικρής υπομονάδας του ριβοσώματος αλλά και ορισμένων εξωριβοσωματικών …