Global ETD Search
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Showing 1 to 3 of 3 for “"Death Effector Domain"”.
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Functional Analysis of the Molluscum Contagiosum Virus MC160 Death Effector Domain-Containing Protein RxDL Motif
… to MCV immune evasion genes. MCV encodes two death effector domain (DED) containing proteins, MC159 and MC160. DEDs are found in cellular proteins such as FADD and procaspase-8. These cellular proteins are involved in several innate immune responses such as apoptosis and activation of …
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Die Rolle des Proteins DEDD in Apoptose
… wie die Todeseffektor-Domäne („death effector domain“, DED), kennzeichnen Moleküle, die Schlüsselfunktionen im Rahmen der Apoptose besitzen. Eines dieser Proteine ist DEDD, das aufgrund seiner starken Konservierung und seiner Abundanz eine Sonderstellung innerhalb der …
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Characterization of the anti-inflammatory effects of the Molluscum Contagiosum MC159 protein
… Mutational analysis revealed that either Death Effector Domain (DED), a protein:protein interaction domain, of the MC159 protein was sufficient for inhibition. Finally, I show homologs of MC159 including MCV MC160 and cellular FLIPL, inhibit IFN-β expression, suggesting DEDs are important …