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Showing 1 to 4 of 4 for “"Daunomycin"”.
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Crystallographic studies of interactions between ligands and DNA oligonucleotides
… experimental section and discussion. The TG4T/daunomycin and G4/daunomycin complexes described in Chapter One are two out of only five crystallographic quadruplex/ligand structures reported to date. In both structures daunomycin molecules stack onto a terminal G quartet preventing the G4 …
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ΑΝΑΛΥΣΗ ΤΩΝ ΑΛΛΗΛΕΠΙΔΡΑΣΕΩΝ ΑΝΘΡΑΚΥΚΛΙΝΩΝ-ΣΙΔΗΡΟΠΟΡΦΥΡΙΝΩΝ ΣΤΟ ΑΙΜΟΠΟΙΗΤΙΚΟ ΣΥΣΤΗΜΑ
ADRIAMYCIN (ADR) AND DAUNOMYCIN (DAU) AUNOMYCIN (DAU) ARE TWO OF THE MOST WIDELY AND USED CHEMOTHERAPEUTIC AGENTS FOR TREATMENT OF VARIOUS NEOPLASMS. HOWEVER,THEIR USE IS LIMITED DUE TO THEIR BONE MARROW (MYELOSUPPRESSION) AND CARDIOVASCULAR TOXICITY. UNFORTUNATELY, IT HASN'T BEEN A UNIFIED THEORY …
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Novel Development of Super-Resolution Force Spectroscopy and Applications in Biological Systems
… and 11 base pairs of DNA duplex with the drug daunomycin. The SURFS technique was used to determine the positions of the ribosome on the mRNA at two distinct states. I found that from the post-translocation state (Post) to the subsequent pre-translocation state (Pre), the ribosome moves …