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Showing 1 to 5 of 5 for “"Dapagliflozin"”.
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Dapagliflozin Regresses Left Ventricular Hypertrophy in People with Type 2 Diabetes
… failure.<br/><br/>We tested the hypothesis that dapagliflozin may regress LVH in people with T2D.<br/><br/>We randomly assigned 66 people (mean age 67 +/- 7 years, 38 males) with T2D, LVH and controlled blood pressure to receive dapagliflozin 10mg once-daily or placebo for 12 months. Primary …
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EFFECTS OF DAPAGLIFLOZIN ON EXERCISE CAPACITY, RESPIRATORY FUNCTION, BIOMARKERS, SLEEP APNEA, AND LEFT VENTRICULAR REMODELING IN PATIENTS WITH HEART FAILURE: A PROSPECTIVE, SINGLE CENTER, NON RANDOMIZED STUDY
Background: Dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, has become a cornerstone in the management of heart failure with reduced ejection fraction (HFrEF). Its clinical efficacy is well-established, primarily attributed to its effects on diuresis and hemodynamic unloading. …
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Epicardial Adipose Tissue: Relationship with Cardiovascular Disease and the Effect of Therapeutic Interventions
… and in REFORM Study in which an SGLT2 inhibitor, dapagliflozin, was given to patients with T2DM and heart failure for 12 months, the impact of these two drugs on EAT area were examined by measuring the EAT area pre and post intervention. <br/><br/>Results <br/>In SUMMIT study, EAT area was found …
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A Comprehensive Analysis of SGLT2-inhibition in Type 2 Diabetes and Heart Failure
… to 19.00; p=0.915 respectively. Patients on dapagliflozin had weight reduction; -1.97kg; 95%CI: -3.99 to 0.05; p=0.056 lower diastolic blood pressure; -6.58mmHg; 95%CI: -11.93 to-1.23; p=0.017 higher haemoglobin; +1.16 g/dL; 95%CI: 0.60 to 1.74; p<0.001 and increased serum …
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Effects of Chronic High Sucrose With Dietary or Drinking Inclusion on the Electrogenic Glucose Absorption in the Intestinal Tract of Mice (Mus musculus)
… Although segmental differences in inhibition by dapagliflozin, an SGLT2 inhibitor or phloridzin dihydrate, an SGLT1 inhibitor were evident, gene expression analysis of the SGLT 1- 6 could not fully explain these regional differences in kinetics. Non-the-less, the kinetics were highly modified by …