Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 127 for “"Danio rerio"”.
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Xenobiotic metabolism and zebrafish (danio rerio) larvae
There is a requirement for the characterisation of the metabolism of xenobiotics in zebrafish larvae, due to the application of this organism to toxicity testing and ecotoxicology. Genes similar to mammalian cytochrome P450 (CYP) 1A1, CYP2B6, CYP3A5 and UDP-lucuronosyl-transferase (UGT) 1A1 were …
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Behaviour and morphology of the zebrafish, danio rerio
… are needed. It is proposed that the zebrafish, Danio rerio, a species well suited to the laboratory environment and with much information available about its genetics, has potential in this area. However, currently little is know about mate choice in this species and whether its behaviour and …
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Characterizing slc8a4b as an Osteoblast Marker in Danio rerio
The solute carrier family 8 member 4b (slc8a4b) is an emerging marker for osteoblasts in zebrafish, enabling further study of healthy bone development, bone regeneration, and skeletal diseases. To guide future use of slc8a4b as an osteoblast marker, this study aims to identify which osteoblast …
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The Effects of noise of Zebrafish (Danio rerio) memory
… noise on the cognitive performance of zebrafish (Danio rerio) and its possible mechanism of action, focusing on GABA neurotransmitter levels in the brain. To this end, adult zebrafish were exposed to four sound treatments: a medium intensity sound presented in either a regular and irregular …
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Modeling and Mapping Addiction in the Zebrafish, Danio rerio
<p>Driven by the communication of dopamine, the vertebrate reward system has been evolutionarily conserved to maintain survival and optimize fitness. The neural circuits governing this system integrate sensory stimuli to produce appropriate, self-preserving responses that underlie experience-based …
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MyosinX is Required For Craniofacial Development in Danio Rerio
<p>Craniofacial development is the process of laying early cartilage and bone patterns in the anterior region of the embryo, which ultimately results in shaping the structure of the face and head of an organism. Craniofacial abnormalities in humans, such as cleft lip and palate, are among the most …
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Alzheimer's disease genes in zebrafish (Danio rerio) / Casper Groth.
… during embryo development using the zebra fish (Danio rerio) as a model organism.
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Ecotoxicogenomic New Approach Methods for Screening Development in Danio rerio
Mankind increasingly relies on chemical compounds, with a significant role they play in various sectors such as technology, medicine, and agriculture. However, this widespread use also raises substantial environmental concerns, particularly regarding unknown adverse effects chemicals such as plant …
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The Effects of Benzyl Alcohol on Developing Zebrafish (Danio rerio)
… effects of benzyl alcohol exposure on zebrafish (Danio rerio), a well-established model for development. Zebrafish were exposed starting at high blastula stage of development (4 hours post-fertilization, hpf) and finishing at free swimming larvae stage (144 hpf). Observations of critical …
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Identifying the Origin of Zebrafish (Danio rerio) Renal Progenitor Cells
The zebrafish kidney can be distinguished from the human kidney by the presence of adult renal progenitor cells (RPCs) that are capable of neonephrogenesis. These cells can be labeled with eGFP in the Tg(lhx1a:egfp) transgenic line. Using this transgenic line, zebrafish kidney regeneration was …
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Multigenerational Neurobehavioural and Reproductive Toxicity of Arsenic in Zebrafish (Danio rerio)
… chronic dietary arsenic exposure in zebrafish (Danio rerio), with a focus on sex-specific susceptibility, epigenetic alterations, and lineage-dependent inheritance patterns. In the first study (Chapter 2), adult zebrafish were exposed to environmentally relevant dietary arsenic concentrations …
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The Neuroinflammatory Effects of Chronic Unpredictable Stress on Zebrafish, Danio rerio
<p>Stress is a state of threatened homeostasis counteracted by various physiologic and behavioral responses aimed to maintain or restore balance. As such, stress acts as a motivator to perform during the challenges of life to survive. Chronic perturbations to the stress response homeostasis without …
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Molecular and Functional Analysis of Otolith Formation in Zebrafish, Danio Rerio
"Mammalian otoconia and fish otoliths are calcium-carbonate biominerals and important inner-ear organs that detect linear accelerations and perceive gravity. As a result, the absence, degradation, or dislocation of these structures causes severe imbalance in affected animals. The common vestibular …
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A Larval Zebrafish (Danio Rerio) Model of Adherent-Invasive Escherichia Coli Infections
… remains unclear. Here a larval zebrafish (<em>Danio rerio</em>) model of AIEC was established, which facilitates the study of the role of pre-existing inflammation, and host- and pathogen- genetic factors during IBD pathogenesis. Paramecium caudatum, a natural prey of zebrafish larvae, was used …
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Individual Differences in Zebrafish (<i>Danio rerio</i>) Behavior: Implications for Personality
<p>Individual differences (IDs) in zebrafish (<em>Danio rerio</em>) behavior were examined across time and contexts in order to investigate personality traits. Zebrafish (N = 30) were exposed to six behavioral tasks that were collectively expected to capture (a) aggression, (b) boldness/shyness, …
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Epigenetic effects of benzo(a)pyrene in Fundulus heteroclitus and Danio rerio
… use two fish models, Fundulus heteroclitus and Danio rerio (zebrafish), to study the benzo(a)pyrene (BaP) effects on DNA methylation status and whether the alterations could contribute to BaP-mediated reproductive and developmental toxicities. Initially, we used Fundulus to study BaP effects on …
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Loss of rad51 in zebrafish (Danio rerio): a novel Fanconi anaemia model
RAD51 is an indispensable homologous recombination protein, necessary for strand invasion and crossing over. It has recently been designated as a Fanconi anaemia (FA) gene, following the discovery of two patients carrying dominant negative mutations. FA is a hereditary DNA repair disorder …
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Auditory Hair Cell Regeneration and Gene Expression in Noise-Exposed Zebrafish (Danio rerio)
Fishes are capable of regenerating sensory hair cells in the inner ear after exposure to excessive noise. However, a time course of auditory hair cell regeneration has not been characterized for zebrafish, nor has gene expression following noise exposure. To establish a time course of hair cell …
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Danio rerio (Hamilton, 1822) širdies ir kraujagyslių sistemos vystymosi ir regeneracinių mechanizmų tyrimai /
Danio rerio (Hamilton, 1822) is a powerful vertebrate model system, which provides a unique combination of advantages that are important for an investigation of cardiovascular development and regeneration. However, conditional mutagenesis, which is essential for dissecting a role of developmental …
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Studying the mechanisms of cardiovascular development and regeneration in Danio rerio (Hamilton, 1822) /
Danio rerio (Hamilton, 1822) is a powerful vertebrate model system, which provides a unique combination of advantages that are important for an investigation of cardiovascular development and regeneration. However, conditional mutagenesis, which is essential for dissecting a role of developmental …
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