Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Daam1"”.
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The Role of Daam1 In Kidney Development
… activator of morphogenesis 1 (Daam1), in shaping nephric tubules. We show that Daam1 governs nephron morphology by regulating E-cadherin-based cell-cell adhesion of progenitor cells and junctional actin filaments' stability. We also report divergent roles for Daam1 in …
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The Role of Daam1 In Kidney Development
… activator of morphogenesis 1 (Daam1), in shaping nephric tubules. We show that Daam1 governs nephron morphology by regulating E-cadherin-based cell-cell adhesion of progenitor cells and junctional actin filaments' stability. We also report divergent roles for Daam1 in …
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Characterisation of the Rho GTPase target Dishevelled Associated Activator of Morphogenesis 1 (DAAM1)
… Associated Activator of Morphogenesis 1 (DAAM1) is a formin which is important for gastrulation. In this thesis, we have sought to characterise DAAM1 in terms of its regulation and function. DAAM1 was found to localise to the perinuclear/Golgi region as well as to the actin/myosin II …
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FUNCTIONAL CHARACTERIZATION OF DENND5A/RAB6IP1 IN EARLY EMBRYONIC DEVELOPMENT
… In Dr. Habas lab, Dennd5a was identified as a Daam1 interacting protein in a yeast two hybrid screen. Daam1 is a key player in non-canonical Wnt signaling and regulates vertebrate gastrulation and neural tube closure. I confirmed that Daam1 can physically bind to Dennd5a in immunoprecipitation …
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Characterization of Dishevelled Associated Activator of Morphogenesis 2 (Daam2) in Wnt Signaling During Early Embryonic Development
… associated activator of morphogenesis 1 (Daam1) was previously characterized as an essential component for non-canonical Wnt-dependent regulation of cytoskeletal reorganization and cell migration. Daam1 and Daam2 are members of the Daam family of proteins but the role of Daam2 in early …