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Showing 1 to 4 of 4 for “"DYRK2"”.

  1. Defining novel targets and functions of the protein kinase DYRK2

    … homology: class I (DYRK1A, DYRK1B) and class II (DYRK2, DYRK3, DYRK4). Remarkable effort has been spent on identifying the roles of human DYRK1A, a Down syndrome candidate gene that is strongly implicated in neurogenesis, yet the physiological functions and substrates of the remaining human DYRK …

    cambridge Repository record for Defining novel targets and functions of the protein kinase DYRK2 (opens in a new tab)

  2. Building a rational model for the identification of allosteric sites

    … site has been determined for the protein kinase DYRK2 using this technique. The potential allosteric pocket was studied through a virtual screen which gave a hit that was successfully prepared and showed good selectivity for DYRK2 over DYRK1A by Differential Scanning Fluorimetry (DSF). This …

    strathclyde Repository record for Building a rational model for the identification of allosteric sites (opens in a new tab)

  3. Modulating Bone morphogenetic protein (BMP) and Transforming growth factor-beta (TGF-β) signalling with green tea catechins in mammalian cells

    … in this research, elevated expression of CALM1, DYRK2, and MPP1 genes have been observed in the nucleus as revealed by their induction of pai-1 and id1-specific target gene expression, also modulating the regulation of specific ligand-induced phosphorylation of SMAD3 and SMAD1/5 proteins …

    bradford Repository record for Modulating Bone morphogenetic protein (BMP) and Transforming growth factor-beta (TGF-β) signalling with green tea catechins in mammalian cells (opens in a new tab)