Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"DSF"”.
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Targeting an E3 ubiquitin ligase Siah1 and a cysteine protease SENP1 using SPR and DSF-based fragment screening
… fragment screening against Siah1 using SPR and DSF are reported in chapter 3. The chapter also presents the structure of Siah1 refined to 1.95 Å that displays new parts of the structure, previously missing due to the absence of reliable electron density. Chapter 4 contains results from the …
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The interaction of disulfiram and H2S metabolism in inhibition of aldehyde dehydrogenase activity and liver cancer cell growth
Disulfiram (DSF) is a sulphur-containing compound and has been used to treat chronic alcoholism and cancer for decades. DSF inactivates aldehyde dehydrogenase (ALDH) by modifying its cysteine residue(s). ALDH is recently identified as a cancer stem cell marker, facilitating cell self-renewal and …
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Kultur als Vehikel : zur Geschichte der Gesellschaft für Deutsch-Sowjetische Freundschaft (1947-1953)
… 'Deutsch-Sowjetische Freundschaftsgesellschaft(DSF)' wurde 1947 als 'Gesellschaft zum Studium der Kultur der Sowjetunion' gegründet, ihre Vorläuferorganisationen in der Weimarer Republik waren die 'Gesellschaft der Freunde des neuen Rußlands' und der 'Bund der Freunde der Sowjetunion'. Der …
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Beyond Arrows: Energy Performance of a New, Naturally Ventilated Double-Skin Facade Configuration for a High-Rise Office Building in Chicago
… ventilation in high rise office buildings with DSF configuration: • A methodology for assessing the performance of naturally ventilated DSF buildings through an airflow modeling was developed by three-dimensional analysis using Fluent. Buoyancy, wind, and combined ventilation strategies for …
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Beyond arrows: energy performance of a new, naturally ventilated, double-skin facade configuration for a high-rise office building in Chicago
… especially true when the new double-skin facade (DSF) configuration is used as a means of conserving energy while providing superior thermal comfort. For these types of buildings, it is important to have the tools to evaluate a design’s predicted performance to achieve successful natural …
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In vitro and in vivo investigation of the anticancer activity and mechanism of disulfiram in malignant mesothelioma
… patient access at a lower cost. Disulfiram (DSF), a Dithiocarbamate-based drug used for the treatment of alcoholism, has shown potential anticancer effects in combination with metal ions (Cu, Zn), primarily due to its ability to generate reactive oxygen species (ROS), inhibit aldehyde …
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The role of bacterial interspecies communication in polymicrobial infection of the cystic fibrosis lung
… molecules of the diffusible signal factor (DSF) family, which are cis-2-unsaturated fatty acids. Previous studies showed that DSF from S. maltophilia leads to altered biofilm formation and increased tolerance to antibiotics in P. aeruginosa and that these responses require the P. aeruginosa …
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Efficient automatic correction and segmentation based 3D visualization of magnetic resonance images
… correction algorithm derivative surface fitting (dsf), automatic tissue detection algorithm (atd), and a new fast technique for interactive 3D visualization of segmented volumes called gravitational shading (gs). These newly developed algorithms provided a foundation for the automated MR …
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An integrated method of environmental assessment coupling a geographic information system to multi-criteria analysis
… and structured decision support framework (DSF) which could aid environmental decision-making. There is no single right way to conduct a decision-making process because every process is limited by resources and timelines. The environmental assessment case study described in this thesis uses …
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Pond hockey dads and climate change : how Canadian fathers feel about the threat of losing the game they love
… It responds to the David Suzuki Foundation’s (DSF) assertion that under a global ‘business as usual’ rate of producing greenhouse gases, the skating season of the world’s largest ‘rink’--the Rideau Canal--would shrink from a nine week historical average to just one week by century’s end (DSF, …
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Improving the performance of polypropylene matrix composite materials using engineered hemp fibre mats
… fibre mats produced using dynamic sheet forming (DSF) to align the short fibres used in the mats. The overall aim of this research was to improve the mechanical performance of hemp fibre mats produced using DSF and to assess the potential of these mats as reinforcement in polypropylene composites. …
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Extending the dielectric formalism in warm dense matter: collisions, dynamic structure factors, and stopping powers
… plasmon peak in the dynamic structure factor (DSF), which can be observed in x-ray Thomson scattering experiments; and the electronic stopping power, which is important for self-heating in ICF. Our results indicate that using collision rates that account for inelastic and strong scattering …
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In vitro investigation of the anticancer activity and molecular mechanisms of action of albumin nano-encapsulated copper/zinc diethyldithiocarbamate in human pancreatic cancer cells
… need for novel, effective therapies. Disulfiram (DSF), an FDA-approved anti-alcoholism drug, has demonstrated potent anticancer activity when chelated with Cu²⁺ or Zn²⁺ ions to form copper diethyldithiocarbamate (Cu(DDC)₂) or zinc diethyldithiocarbamate (Zn(DDC)₂). However, the clinical anticancer …
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Towards a Trustworthy and Decentralised Future Internet of Things
… end-to-end secure decentralised applications (DSF), then building on this to address the need for e cient and unambiguous speci cations for describing, (locally) discovering, and interacting with IoT services to create a decentralised platform for IoT devices (DSF-IoT). We then extend this work …
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Decision support for the operational planning phase of the transit network planning problem
… (VCRPST). A novel decision support framework (DSF) is proposed in this dissertation for aiding planners during the operational planning phase of attempts at solving instances of the TNPP. The DSF is designed to provide a structured and adaptable guide for assisting transport planners with the …
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Assessing dry spell and wet day frequencies over southern Africa during the summer rainy season
… Madagascan highlands where dry spell frequency (DSF) (moderate wet day frequency (MWDF)) tended to be relatively lower (higher). A region which frequently experienced half of the season as dry was identified lying across 22-24◦S (18-25◦S) during DJF (MA), with a core in the central Limpopo River …
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Present-day and late Quaternary crustal deformation along the southern Dead Sea Fault System, Jordan
… region. Two main segments comprise the southern DSF: the Wadi Araba and Jordan Valley faults. These two main fault branches are separated by a left step-over that forms the Dead Sea basin. This study incorporates new GPS measurements in Jordan (survey-mode and continuous), as well as recently …
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Properties and applications of double-skin building facades
… The common elements are double-skin facades (DSF's) that employ sun shading and air movement between inner and outer glass membranes. The doubleskin or "airflow" facade is tied to mechanical systems either physically with ducts or by significantly affecting the performance of those systems by …
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The effects of invasive slender false-brome (Brachypodium sylvaticum) on forest ecosystem function in western New York
… Trumansburg, and one in Danby State Forest (DSF), Danby. Replicate paired plots with and without B. sylvaticum were selected in each forest; each pair was matched by canopy cover and canopy type. In plots I measured vegetation, soil physical and chemical characteristics, soil moisture, soil …
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Integrated Thermal and Daylight Performance Comparison of Single and Double Glass Skin Facade for Hot Climate Conditions
… elevation. In fact, the double-skin façade (DSF) offers transparency while reducing energy consumption when compared to single-skin systems in cold and moderate weather conditions. However, there is no clear evidence of how the system will perform in hot climate conditions. In this research, …
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