Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 99 for “"DRG"”.
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Alleviating ribosomal stalls: functional characterization of conserved Drg GTPases
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01
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Macrophage recruitment in DRG contributes to sensory axon regeneration after conditioning injury
The central branches of the dorsal root ganglia (DRG) sensory neurons do not spontaneously regenerate. It has been known that the sensory neurons can regenerate if their peripheral branches are severed before SCI (conditioning injury, CI). After peripheral nerve injury, macrophages accumulate in …
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Darstellung stationärer Behandlungskosten im Rahmen der leistungs- und DRG-bezogenen Abrechnung an der Universitäts-Hautklinik Freiburg : eine Pilotstudie
Mit Einführung des DRG-Systems müssen in den deutschen Krankenhäusern defizitäre Kostenstrukturen aufgedeckt und die Kostentransparenz erhöht werden. Daher wurde in der Universitäts-Hautklinik anhand von zehn Stichproben mit je 20 Falldaten eine diagnosebezogene Kostenträgerrechnung durchgeführt. …
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Vergleich einer DRG-bezogenen Leistungsabrechnung mit der Vergütung nach Tagespauschalen und deren Konsequenzen für die Universitäts-Hautklinik Freiburg
… Entgeltsystems auf Grundlage der AR-DRGs in den deutschen Akutkrankenhäusern beschlossen. Die vorliegende Arbeit untersucht die Frage, wie sich der Vergleich einer DRG-bezogenen Abrechnung mit der Vergütung nach Tagespauschalen darstellt und welche Konsequenzen sich daraus für die …
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Benefits derived from capturing consumable supply costs by DRG as an input to physician practice pattern programs in military treatment facilities
The study examines the benefits that can be derived by Military Treatment Facilities from capturing consumable supply costs by Diagnostic Related Groups. Civilian hospitals are capturing supply costs at the patient level using physician and Diagnostic Related Grouped specific cost accounting …
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Medizinethische Aspekte der fallpauschalisierten Abrechnung im deutschen Krankenhauswesen
… Die Abrechnung erfolgt nach sogenannten DRG (diagnosis related groups). Die Studie untersucht die Einführung des DRG-Systems multidimensional am Beispiel von Patienten mit einem Bronchialkarzinom und ihren behandelnden Ärzten und Pflegekräften. Die empirische Untersuchung gliedert sich in …
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CRISPR/Cas9 screenings and in silico investigations nominate low-frequency alterations in DNA repair genes as biomarkers for castration-resistant prostate cancers.
… for the covered non-BRCA DNA repair gene (DRG) aberrations, and the duration of the treatment response is highly heterogeneous among responders. In this scenario, in the present study we aimed at the identification and characterization of novel low-frequency DRG alterations that could …
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Diffuse axonal injury effect on myelinating cells and axons
… their axons myelinated. Dorsal root ganglion (DRG) neurons have been shown to be myelinated by cortical oligodendrocytes in culture. An in vitro stretch injury model was used to analyze the DRG axon pathology during and after injury. DRG myelinating Schwann cells are analyzed to demonstrate …
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Investigating the assembly of axonal domains for saltatory conduction
… (PS), in peripheral Dorsal Root Ganglion (DRG) neurons. Neurofascin B (NfascB), a zebrafish cell adhesion molecule homologue of the murine glial protein Neurofascin155 (Nfasc155), prevents aberrant myelination of neuronal cell bodies in the CNS. Moreover, NfascB and its axonal partner, …
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A Study of Pro- and Anti-Nociceptive Factors In A Model of Colitis-Associated Visceral Pain
… factors regulating colonic dorsal root ganglion (DRG) neurons, which synapse onto second order dorsal horn neurons, are known to regulate chronic pain but the mechanisms are poorly understood. This thesis examined whether neuroanatomical remodeling of DRG central nerve terminals underlies …
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Acrolein as a novel therapeutic target for spinal cord injury induced neuropathic pain
… receptor potential ankyrin 1 receptor (TRPA1) in DRG nociceptive neurons to transmit pain sensation. In addition, we have observed a significant increase of monocyte chemoattractant protein-1 (MCP1), a pro-inflammatory chemokine that is also known be increased upon acrolein stimulation and capable …
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Clinical and financial evaluation of patients within a diagnosis related group
… and clinical data of patients within a selected DRG. The data obtained from such analysis will be used to design a system whereby clinical pharmacists may improve the hospital's reimbursement potential.</p><p>Based upon Upton's proposed plan, this study is designed to evaluate all DRGs in a …
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The Sandwich Synapse: Trans-glial Signaling Between Neuronal Somata in the Dorsal Root Ganglion
The dorsal root ganglion (DRG) contains the cell bodies of primary somatosensory neurons that form axonal connections for the transfer of sensory input from the peripheral nerve receptor to the spinal cord in the central nervous system. In general, DRG neuronal somata (NS) are each enveloped by …
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A novel surgical tool for stimulation paddle delivery to the dorsal root ganglion of the spine
Dorsal root ganglion (DRG) stimulation is a novel method of treating chronic pain in which a lead with a set of electrodes is placed on the nerve root of the spinal cord above the pain site. This method shows promise over traditional spinal cord stimulation due to the its localized nature as …
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Assessing the Role of the Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channel in Visceral Sensation
… in colon-projecting dorsal root ganglion (DRG) neurons and colonic nerve terminals, as well as functional activity at the neuronal and nerve levels. TRPM3 protein expression was observed in 76.1 % of colon-projecting DRG neurons and TRPM3 was also present in putative axons within the mouse …
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Characterization of an Alternatively Spliced Platelet-Derived Growth Factor Variant During Myelin Synthesis
… was detected in rat dorsal root ganglion (DRG) neuron/Schwann cell cocultures and shown to regulate myelin synthesis. mRNA transcripts of the long-form PDGF-A chain variant (LF-PDGF-A) were detected by RT-PCR in cocultures. Its expression level increased during active myelin synthesis in …
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Alzheimer's Disease and Amyloid Beta: Effects of amyloid beta on hippocampal and dorsal root ganglion neurons' electrophyiology and morphology
… isolated hippocampal and dorsal root ganglion (DRG) neurons in order to test whether the effects of Aβ exposure and clearance are exclusive to central nervous system neurons. Isolation and culture of hippocampal and DRG neurons were performed. By exposing neurons to combinations of Aβ42 and …
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Case mix and coding error detection in Western Cape healthcare facilities
… the first steps towards Diagnosis Related Group (DRG) to categorise hospitalisation costs in the public health facilities in South Africa. DRG's are widely used in the private sector for active cost management. Additionally, an issue was raised by the on-site audit clinical coding report of the …
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Forced-Exercise Alleviates Neuropathic Pain in Experimental Diabetes: Effects on Voltage-Gated Calcium Channels
… (VGCC) in small diameter dorsal root ganglion (DRG) neurons. Using behavioral, nerve-electrophysiology and patch-clamp methodology we examined the functional consequences of forced-exercise (treadmill, 5.4 km/week) on VGCC in dissociated small diameter DRG neurons from rats conferred diabetic by …
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