Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"DRD4"”.
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Exploring Interactions Between DRD4 Genotype and Perceived Parenting Environment
This study examined possible interactions between DRD4 genotype and parenting on children’s externalizing, internalizing, and prosocial behaviors, and explored both parent and child perceptions of all variables. Both diathesis-stress and differential susceptibility hypotheses were assessed for …
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5-HTTLPR, DRD4 gene, college students’ psychological characters and academic performance
… evaluate associations between the 5-HTTLPR, the DRD4 gene, psychological characteristics including metacognition and depression, and academic performance as reflected in SAT scores. We discovered that participants with 2-repeat or 7-repeat alleles of the DRD4 gene have significantly lower scores …
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Polymorphisms in Dopamine System Genes DAT1 and DRD4 are Associated with Disinhibitory Psychopathology in Adolescence
… polymorphisms in the dopamine receptor D4 (DRD4) and dopamine transporter (DAT1) genes and the symptoms and diagnoses of ADHD, ADHD subtypes, oppositional defiant disorder (ODD), and conduct disorder (CD) in 2902 individuals from a population-based twin sample. We observed an association …
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The genetics of sports behaviour : the role of the DRD4 gene in sensation seeking in skiers
… trait is the dopamine-4-receptor gene (DRD4), in which variants have been associated with sensation seeking and novelty seeking in some, but not all studies. The inconsistencies between studies may be due to heterogeneity in both the behaviours and the populations being assessed. Some …
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Molekulargenetische Aspekte dopaminerger Modulation der Responsivität gegenüber Neuheit
… ein Polymorphismus des Dopamin-D4-Rezeptor-Gens (DRD4 Exon III). Nichtsdestoweniger ist seine funktionelle und verhaltenswirksame Rolle bisher weitgehend unklar: Zwar wurden bestimmte Varianten des Polymorphismus mit einer höheren Ausprägung in der Temperamentsdimension Novelty Seeking in …
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Genetic and environmental influences on impulsivity and coping motives for alcohol across emerging and young adulthood
… in the gene encoding the dopamine D4 receptor (DRD4) may moderate the influence of environments (i.e., a gene-environment interaction, GXE) on personality traits and motives associated with alcohol use disorders. This project examines whether variation in DRD4 moderates the environmental …
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Vulnerability to substance dependence
… populated and having the long variant at the DRD4 gene was found to predispose individuals to a high lmpSS personality type. Moreover, genotype alone predicted ImpSS behaviour amongst the heroin group, shedding light onto the controversy surrounding the influence of DRD4 on ImpSS behaviour and …
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BIOLOGICAL AND ENVIRONMENTAL PREDICTORS OF EXTERNALIZING BEHAVIOR IN LATE CHILDHOOD AND ADOLESCENCE: A TWIN STUDY
… presence of specific dopamine receptor (DRD2 and DRD4) risk alleles, and delinquent peers or siblings would be related to increased externalizing behavior at follow-up. The sample consisted of 65 twin pairs, aged six to 16 (mean age = 9.06 years) who originally participated in the Southern …
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The impact of serotonergic and dopaminergic genetic variation on endophenotypes of emotional processing
… a poly-morphism in the dopamine receptor 4 gene (DRD4) in the same sample of young adults with regard to the cortisol stress response with carriers of the DRD4 7R allele which has been associ-ated with higher scores in sensation seeking, showing reduced cortisol responses. In addition, a 5-HTTLPR …
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The effect of genotype on attention bias in rhesus macaques, Macaca mulatta, as a welfare indicator.
… identify novel SNPs in the dopamine receptor D4 (DRD4). The 5-HTTLPR short-, TPH2 long-, MAOA 7-repeat and OPRM1 G-allele are low-expressing alleles leading to lower levels of circulating neurotransmitters in the brain, and have been shown to be linked to anxiety, coping mechanisms and …
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Impact of the Serotonin-Transporter-Polymorphism (5-HTTLPR) and Stressful Life Events on the Stress Response in Humans
… dopaminergic system, the dopamine D4 receptor (DRD4) was included to consider these likely gene-gene interactions (epistasis). The aim of this series of studies was to investigate the role 5-HTTLPR and SLEs on the endocrine stress response in different age samples. While newborns have been …
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Interaction Effects between the Cumulative Genetic Score and Psychosocial Stressor on Drinking Urge and Attentional Bias for Alcohol: A Human Laboratory Study
… the cumulative genetic index of 5-HTTLPR, MAO-A, DRD4, DAT1, and DRD2 genotypes (candidate genes and environment interaction; cGxE). The current study also examined whether salivary alpha-amylase level or anxiety state mediate the cGxE effects. One hundred five Caucasian young adults (mean age = …
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Psychological and Genetic Contributions to the Development of Social Cognition in Children
… who had at least one risk allele in both the DRD4 and the 5-HTTLPR polymorphisms would perform worse than those who had at least one risk allele in either polymorphism, who, in turn, would perform worse than children without any risk alleles. The twin sample included 62 families of multiples …
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Considering behaviour in genetic sampling – a case study with grey seals
… identify polymorphisms; a SNP in the grey seal DRD4 gene not previously reported in any other studies was found. However, some inconsistent results from PCR amplification and Sanger sequencing suggest that further technical development is necessary before it can be reliably used in an efficient …
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Quantitative Genexpressionsanalyse im respiratorischen Netzwerk an Mausmodellen für das Rett-Syndrom
… Htr4 (P7) und als Aktivator auf Grin2d (P7), Drd4 (P7), Oprm1 (P40) wirken könnte. Sehr starke Evidenzen weisen daraufhin, dass Htr5b und Foxp2 ebenfalls Zielgene von MeCP2 sind und dass MeCP2 supprimierend auf deren Expression wirkt. Um die Zusammenhänge zwischen MeCP2 und seinen Zielgenen …
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Dopamin und kognitive Handlungssteuerung: Flexibilität und Stabilität in einem Set-Shifting Paradigma
… (EBR), die Polymorphismen COMT Val-158-Met und DRD4 Exon III sowie das Geschlecht eingesetzt. In der dritten Studie sollte eine Dopaminausschüttung experimentell durch die Darbietung von Signalen einer potenziellen Belohnung (Geldgewinn) stimuliert werden. Hierdurch sollten die beobachteten …
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The molecular genetics of bipolar affective disorder : South African populations, endophenotypes, and environmental influence
… VNTR polymorphism in the dopamine 4 receptor (DRD4) gene was associated with '""Memory"" performance. As a third strategy, a potentially important aetiological factor, childhood trauma, was measured, and used to test for gene-environment interactions between the various candidate genes and …
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Dopaminergic Genetic Contributions to Obesity in Kidney Transplant Recipients
… SNP rs6280, dopamine receptor type 4 gene (DRD4) variable number tandem repeat (VNTR), catechol-o-methyltransferase gene (COMT) SNPs rs4680 and rs4818, monoamine oxidase A gene (MAOA) VNTR, monoamine oxidase B gene (MAOB) SNP rs1799836, and dopamine active transporter gene (SLC6A3/DAT1) …