Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"DOSY"”.
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De Novo Design and Stabilization of β-Sheet Peptides for Biomimicry of ORR Enzymes
… resonance (EPR), diffusion-ordered spectroscopy (DOSY), and single-crystal X-ray diffraction (SC-XRD). The peptides are analyzed both in their apo and metalated forms. This work features the first crystallographic evidence for a metallo-β-sheet peptide. Chapter three introduces a macrocyclization …
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Synthesis and Physical Properties of Helical Nanosized Quinoline-based Foldamers: Structure, dynamics and photoinduced electron transport
… conformation state of foldamers in gas phase; DOSY and fluorescence anisotropy assessed the diffusion (translational and rotational, respectively) of foldamers in solution. All of these techniques revealed that quinoline-based foldamers are rigid and that helical conformation is conserved. …
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Development and Application of NMR Diffusometry and Relaxometry Methodologies to Study Organic-Inorganic Interactions at Nanomaterial Surfaces
… binding of perovskite QDs via utilization of DOSY NMR to quantify changes to their surface dynamics as a function of QD composition. These results showed that by increasing the concentration of iodide ions in the CsPbBr<sub>3x</sub>I<sub>x</sub> lattice yielded a concurrent drop-off in surface …
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High-Resolution Nuclear Magnetic Resonance Microspectroscopy
… in microcoils. Diffusion-ordered spectroscopy (DOSY) experiments, which allow spectral simplification arising from differences in diffusion coefficient, coupled with conventional chemical shift and scalar coupling differences, were shown for the first time for mass-limited samples.
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Nuevas perspectivas en procesos organocatalizados promovidos por enlaces de hidrógeno
… de experimentos 2D RMN, particularmente DOSY, se ha puesto de manifiesto cómo la prolina y la sal de guanidinio forman agregados supramoleculares de diferente tamaño, asociados por enlace de hidrógeno, cuyo papel es determinante en el curso de la reacción. De este modo, y por primera vez, …
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Synthesis and characterization of terpyridine-based fluorescent coordination polymers
… been established by 1H NMR and additionally by DOSY NMR and fluorescence anisotropy measurements. Coordination polymer strands can be visualized by atomic force microscopy (AFM), which also reveals the formation of an ordered monolayer film at higher concentration. The average polymer length has …
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Homocystéine et ferritine: facteurs de risque additionnels des maladies cardiovasculaires chez la femme ménopausée
La prévalence des maladies cardiovasculaires (MCV) double chez les femmes après la ménopause, stade de la vie caractarérisé par la perte des effets protecteurs de la sécrétion d'oestrogène. Des facteurs athérogéniques additionnels s'ajoutent à l’influence de ce changement hormonal sur les …
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Exploiting cooperative effects in s-Block organometallics for new applications in synthesis and catalysis
… crystallographic and NMR studies (including DOSY NMR).The second part of this thesis assesses cooperative effects of single-metal organomagnesium complexes in deprotonation and C-F bond activation processes.Using a specially designed metallating base, which combines within the same molecule a …
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The asymmetric synthesis of enol phosphates and their application in total synthesis
… of the reactive species in solution through DOSY NMR techniques were also carried out. Finally the sum of knowledge gained through synthesis and application of enolphosphates allowed the total synthesis of a natural product (+)-Sporochnol. The key transformation of the synthesis consisted on …
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Understanding the Role of Anisotropy on the Optoelectronic and Colloidal Properties of Quantum Rods for Programmable Self-Assembly with DNA Origami
… two-dimensional diffusion ordered spectroscopy (DOSY) and relaxation ordered spectroscopy (ROSY). My work revealed that as the aspect ratio increases, there’s a transition of ligand binding from a tightly bound and close-packed monolayer model to a sparse, weakly bound, flat and wrapping system. …
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Mechanistic Understanding of Co-crystal solubility and dissolution by using a combination of Experimental and Molecular Modelling Techniques
… (NMR) and Diffusion Ordered Spectroscopy (DOSY). It was found that the type of a polymer, its concentration, and the interaction of the polymer with a co-former in solution will significantly affect the FFA and CBZ co-crystals (4). Molecular modelling of free drug molecules with coformers …
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Insight into Nucleation Kinetics of Flufenamic Acid Cocrystal Formulation in Solution: Investigating the Role of Polymeric Excipients through Combined Experimental and Computational Approaches
… disruption of FFA dimer formation. DOSY NMR experiments revealed polymer-dependent diffusion effects, PVP-VA and SOL significantly increased FFA mobility. PEG, in contrast, showed minimal enhancement of diffusion, instead acting as a stabiliser. Combinations of PVP-VA with PEG or SOL …
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Zinc(II) Schiff Base Complexes and their Aggregation/Deaggregation Properties: Versatile and Multifunctional Materials as Chemosensors and Building Blocks for New Supramolecular Architectures
… un approccio combinato di spettroscopia 1H NMR, DOSY NMR, d assorbimento e di fluorescenza, si osserva che queste specie formano sempre aggregati in soluzione di solventi non-coordinanti. Il grado di aggregazione dipende dalla natura del ponte diamminico. In solventi coordinanti o in presenza di …
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Design, synthesis and biological evaluation of bioorganometallic metallarectangles
… using an array of spectroscopic (1H, 13C, DOSY NMR, and FT-IR spectroscopy) and analytical (ESI-MS and melting point analysis) techniques. The known, corresponding 4,4'-bipyridine analogues were also synthesized to evaluate the pharmacological effects of incorporating the quinoline …
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Self-assembly of synthetic and biological components in water using cucurbit[8]uril
This thesis discusses progress made towards assembling molecular building blocks in the presence of our molecular host of choice, cucurbit[8]uril (CB[8]). Our studies on the self-assembly of synthetic and biological components in water bridge overlapping concepts and techniques drawn from the …
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The Greener Alternative: Sustainable Development in Iron Catalysis and Biodegradable Polymers
… (GB) materials are characterized through 1H and DOSY NMR spectroscopy, FTIR, and solubility. We employ sodium hydroxideto activate the polysaccharide and promote solubility in the reaction media. Cation species have a strong influence on activation which follows trends from the Hofmeister series. …
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Metal complexes with ω-alkenyl ligands. synthesis, structure, reactivity, and applications in chemical vapor deposition (CVD) and hydrosilylation catalysis
… NMR resonances of the olefinic hydrogen atoms. DOSY and NOE measurements show that (2,2-dimethylbut-3-en-1-yl)lithium and (2,2-dimethylpent-4-en-1-yl)lithium remain tetrameric in cyclohexane and that the lithium-olefin interactions persist in solution. Addition of a Lewis base such as THF to …