Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"DOPA decarboxylase (DDC)"”.
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Comparative analysis of Anopheles gambiae L-tyrosine decarboxylase and L-DOPA decarboxylase
A major pathway of tyramine and dopamine synthesis in insects is through the decarboxylation of tyrosine and DOPA, respectively. Although tyrosine decarboxylase (TDC) has been mentioned in some reports, it has never been critically analyzed. The high sequence identity shared by tyrosine …
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Simulating biochemical physics with computers
… The second part is to investigate the role of dopa decarboxylase (DDC) in the catalysis of converting anti-Parkinson drug L-dopa into dopamine. By means of combined QM/MM potentials in MD simulations, we first analyze the factors contributing to the tautomeric equilibrium of an intramolecular …
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Mass Spectrometric Analysis of Tyrosine Metabolic Enzymes
… by many well-characterized enzymes including dopa decarboxylase and tyrosine hydroxylase. On the other hand, there are still many enzymes involved in these processes that we know very little about. Dopachrome tautomerase (DCT), dopachrome conversion enzyme (DCE) and α-methyldopa resistant …
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Biochemical Studies of Aromatic Amino Acid Decarboxylases and Acetaldehyde Synthases
… of PLP-dependent enzymes, aromatic amino acid decarboxylases play critical physiological roles because many aromatic amines are essential neurotransmitters. This dissertation concerns the biochemical characterization of several PLP-dependent decarboxylases and aims to understand the …
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Transcriptomic Profiling of Hypothalamic Kiss1 Neurons
… of serotonin and all catecholamines, dopa decarboxylase (Ddc), was selectively ablated in Kiss1 neurons using CRE-Lox technique. There was no observable difference in fertility and fecundity parameters between wild-type and knockout mice. Thus, the role of serotonin and catecholamine …
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The epigenetics and role of Dopa Decarboxylase in heart development
… on the parent-of-origin of that allele. The Ddc_exonla gene transcript is under the control of genomic imprinting in the developing and neonatal mouse heart with transcription occurring solely on the paternally inherited allele, with the maternally inherited allele epigenetically silenced. In …