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Showing 1 to 1 of 1 for “"DNMT1, DNA methylation, HPV-16, cervical cancer, PCNA, Hsp70"”.
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The roles of DNA(cytosine-5) methyltransferase1 in carcinogenesis related to cellular factors, virus and chemicals
Infection with HPV-16 genomes which is a primary cause of cervical cancer was shown to be targeted in-vivo by CpG methylation. In a clinical study it was discovered that genomic hypomethylation of the LCR and promoter region correlated with carcinogenic progression. The HPV-16 genome could be …