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Showing 1 to 2 of 2 for “"DNAM-1"”.

  1. Exploring Veto Activity: DNAM-1-CD155 Axis in Overcoming NK Cell-Mediated Allo-Rejection and Applications for CAR-T Cell Therapy

    … a primary ligand for the activating receptor DNAM-1. Later in vitro studies further indicated that conjugation between veto Tcm cells and alloreactive NK cells induces NK cell anergy by enhancing the internalization and degradation of DNAM-1, a process significantly linked to the activation of …

    uthsc Repository record for Exploring Veto Activity: DNAM-1-CD155 Axis in Overcoming NK Cell-Mediated Allo-Rejection and Applications for CAR-T Cell Therapy (opens in a new tab)

  2. Interaktionen von dendritischen Zellen und Effektorzellen der frühen antitumoralen Immunabwehr

    … (NKp46, NKp44, NKp30) und Korezeptoren (2B4, DNAM-1) auf NK-Zellen demonstriert, welche essentiell für die NK-Zell-vermittelte Erkennung und Lyse von Tumorzellen sind. In weiteren Untersuchungen induzierten LPS-aktivierte slanDCs eine erhebliche Produktion von Interferon (IFN)-gamma in …

    qucosa-diss