Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"DNA-immunization"”.
-
Single chain MHC trimer-based DNA vaccines for pathogen protection
… strategy for successful vaccines. However, most immunization approaches with class I binding peptides have failed to induce CD8+ T cell responses strong enough to prevent disease. This failure has been attributed to the lack of CD4+ T cell help and difficulty in maintaining a sufficient level of …
-
Alpha-Fetoprotein-spezifische Immuntherapie des hepatozellulären Karzinoms mittels DNA-Immunisierung
… vielen HCCs exprimiertes Tumorantigen. Mittels DNA-Immunisierung wurden in der Maus Immunantworten autoreaktiver zytotoxischer T-Zellen (CTLs) gegen Maus-AFP (mAFP) erzeugt und untersucht. Dafür wurden rekombinante mAFP-exprimierende DNA-Plasmide und Vakziniaviren hergestellt. In einem murinen …