Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"DNA-hydrolyzing activity"”.
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Functional stability of a nucleic acid-hydrolyzing single chain antibody in various biochemical and biophysical environments
… fragment (scFv) antibody has cell-penetrating activity, nucleic acid-binding activity, nucleic acid-hydrolyzing activity, and antiviral activity. As a first step toward development of antiviral reagent using 3D8 scFv, functional stability based on DNA-binding and -hydrolyzing activity of 3D8 …
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Effect of disruption of 3D8 complementarity-determining regions on properties of 3D8 antibody
… of light chain by (G4S1)3 linker) which has DNA-binding/-hydrolyzing, heparin-binding and cell-penetrating activities. We generated single CDR-disrupted antibodies in the formats of scFv (sc-H/LCDRi; inactivated-CDR of variable domain of heavy or light chain in scFv format), VH (H-CDRi; …