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Showing 1 to 2 of 2 for “"DNA-binding drugs"”.

  1. Novel Development of Super-Resolution Force Spectroscopy and Applications in Biological Systems

    … unique biophysical applications in studying drug-DNA interactions and ribosomal translocations. I demonstrate that SURFS has a high force resolution of 0.5 pN by resolving the dissociation forces of 12 base pairs of DNA duplex and 11 base pairs of DNA duplex with the drug daunomycin. The SURFS …

    houston Repository record for Novel Development of Super-Resolution Force Spectroscopy and Applications in Biological Systems (opens in a new tab)

  2. Electrochemical detection of interactions between DNA and various ligands

    Antibodies specific for DNA, with varying degrees of sequence specificity, are common in many autoimmune diseases including systemic lupus erythematosus. The presence of anti-DNA antibodies is a useful determinant in arriving at a prognosis in these conditions. Given the prevalence of these …

    sask Repository record for Electrochemical detection of interactions between DNA and various ligands (opens in a new tab)