Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 132 for “"DNA-based"”.
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DNA–based data storage system
… room at the bottom”. Among known macromolecules, DNA is unique insofar as it lends itself to implementations of non-volatile recording media of outstanding integrity and extremely high storage capacity. The basic system implementation steps for DNA-based data storage systems include synthesizing …
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Next generation DNA-based data recorders
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-05-01
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DNA based biosensors for environmental and medical applications
In the present thesis two electrochemical DNA based biosensors were developed using screen printed electrode as transducers. Biosensors are defined as a self-containing integrated devices, capable of providing specific quantitative or semi-quantitative analytical information using a biological …
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Rational Design of DNA-Based Lipid Membrane Pores
DNA nanotechnology has revolutionised our capability to shape and control three-dimensional structures at sub-nanometre length scales. In this thesis, we use DNA to build synthetic membrane-inserting channels. Porphyrin and cholesterol tags serve as membrane anchors to facilitate insertion into the …
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DNA-based Artificial Mimics of Cell-surface Machinery
… hosted by their biological counterparts. DNA nanotechnology has emerged as a prime route for biomimicry given its yet unparalleled control over the structure and dynamic responses of synthetic nanostructures. Particularly promising in the context of bottom-up synthetic biology is the …
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DNA based networks, nanostructures, and meta-stable states
… important materials is deoxyribonucleic acid (DNA). DNA has several unique properties that make it a good candidate for nanotechnology research. The primary aim of this research is to use DNA three-way junctions as building blocks and to assemble them into a huge DNA networks through self …
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Methods for the development of a DNA based nanoelectronics
The exceptional self-assembly properties of DNA as well as its ability to interact with different kinds of chemical compounds and biological structures make this biomolecule to an interesting object for the fabrication of artificial nanostructures. In this work several methods for a DNA-based …
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Improving Reliability in DNA based Computations with Applications to Cryptography
DNA computing has become an attractive alternative to traditional computing techniques due to the large storage capacity of DNA, massive parallelism and energy efficiency of the computations. However, since DNA computing is based on bio-molecular reactions, it is not error free. One of the main …
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Extracellular DNA-Based Trapping of Heavy Metals by Root Border Cells
… have revealed that, as in animals, extracellular DNA (exDNA) trapping plays a central role in defense, but the mechanism remains poorly understood. Upon immersion in water, border cells and the associated exDNA mucilage structures rapidly disperse and are primed for function in defense of the root …
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Development of Functional DNA -Based Sensors and Investigations Into Their Mechanism
… of a successful functional nucleic acid-based sensor is its isolation and this is done through in vitro selection. In vitro selection to isolate DNAzymes for Hg2+ and Cd2+ and the use of negative selections to overcome Pb 2+ interference at various stages of selection has been described …
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Development of functional DNA-based sensors and investigations into their mechanism
… paradigm in nucleic acid chemistry. Catalytic DNA molecules also known as deoxyribozymes or DNAzymes were first isolated in 1994 through an in vitro selection procedure and have since been engineered and isolated to perform various functions that include both RNA and DNA cleavage and ligation. …
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DNA-Based Mimics of Membrane Proteins Lipid-DNA Interactions Determine Function
Nucleic acids, particularly DNA, are used as a nanoscale building material, due to their unique controllability via complementarity of base pairing. One of the potential applications of DNA nanotechnology is creating synthetic constructs mimicking function of membrane proteins. These natural …
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A study of nanostructured materials toward coronary artery stenting and DNA-based biosensing
… Nanocoatings were further modified with NH3+O2-based glows; these glows introduced potentially therapeutic chemical groups into the nanocoating. In vitro cell cultures confirmed the coatings promoted suitable endothelialization while minimizing the potential fr thrombosis. Surface chemical and …
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DNA-based Population Estimation, Harvest Vulnerability, and Home Range Dynamics of Black Bears in Western Maryland
… of bear hair during summer 2011. We used a model-based sampling design that allowed us to collect samples more efficiently. We used presence-only maximum entropy (Maxent) modeling to classify the study area based on predicted probability of bear occurrence, and allocated the majority of our hair …
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Programmable biomolecular integration and dynamic behavior of DNA-based systems for development of biomedical nano-devices
… role as a carrier of genetic information, DNA has emerged as an engineering material for construction of nano-devices. The advances in the field of DNA nanotechnology have enabled design and synthesis of DNA nanostructures of arbitrary shapes and manipulation of the nanostructures' …
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The development of Deoxyribonucleic Acid (DNA) based methods for the identification and authentication of medicinal plant material.
… neither of which are ideal. A wide range of DNA based methods have been applied to this arena, standardisation is required to realise the potential of DNA based techniques. The DNA barcoding initiative aims to produce sequence data for all plant species, capable of species identification. The …
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Identification of Species in Ground Meat Products Sold on the U.S. Commercial Market Using DNA-Based Methods
… both supermarkets and specialty meat retailers. DNA was extracted from each sample in duplicate and tested using DNA barcoding of the cytochrome c oxidase subunit I (COI) gene. The resulting sequences were identified at the species level using the Barcode of Life Database (BOLD). Any samples that …
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From metacommunity dynamics to rapid biodiversity assessment: DNA-based approaches expand horizons in both fundamental and applied ecology
… and beta diversity information, and reference-based OTU-picking is demonstrated to be a useful approach where there is interest in the responses of a particular set of species. Potential applications and current limitations are discussed in Chapter 8.
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Population structure of lake trout (Salvelinus namaycush) In Atlin Lake, British Columbia and contributions to local fisheries: a microsatellite DNA-based assessment
… lake trout populations at eight microsatellite DNA loci and for body morphology to determine: (i) the level of genetic variation present, (ii) the level of substructure that occurs in Atlin Lake, and (iii) whether there was a relationship between the genetic and morphological variation present. …
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