Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"DNA replication licensing"”.
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KSHV encoded viral processivity factor, ORF59, regulates multiple pathways for viral replication
… at risk for developing lethal cancers. ORF59, a DNA processivity factor of the viral DNA polymerase, is essential for lytic reactivation and is highly expressed during de novo primary infection. To better understand the role of ORF59, we performed an ORF59-immunoprecipitation from KSHV infected …
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Proteomic profiling of matched normal and tumour tongue biopsies from smokers and non-smokers. Oncoproteomic applications for oral tongue squamous cell carcinoma biomarker discovery
… Cytoskeletal 8 (KRT8), Lipocalin-1 (LCN1) and DNA replication licensing factor MCM2 (MCM2) were identified as biologically associated with smoking compared to non-smoking, providing viable targets for verification by immunochemical methods which further supported the proteomic data. Overall, …
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Proteomic profiling of matched normal and tumour tongue biopsies from smokers and non-smokers. Oncoproteomic applications for oral tongue squamous cell carcinoma biomarker discovery
… Cytoskeletal 8 (KRT8), Lipocalin-1 (LCN1) and DNA replication licensing factor MCM2 (MCM2) were identified as biologically associated with smoking compared to non-smoking, providing viable targets for verification by immunochemical methods which further supported the proteomic data. Overall, …
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Proteomic profiling of matched normal and tumour tongue biopsies from smokers and non-smokers. Oncoproteomic applications for oral tongue squamous cell carcinoma biomarker discovery
… Cytoskeletal 8 (KRT8), Lipocalin-1 (LCN1) and DNA replication licensing factor MCM2 (MCM2) were identified as biologically associated with smoking compared to non-smoking, providing viable targets for verification by immunochemical methods which further supported the proteomic data. Overall, …
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Spatiotemporal dynamics of cell division in intestinal homeostasis
… crypt compartments by investigating the DNA Replication Licensing System. The licensing system is a master regulator of proliferative fate in all cells in adult tissue. At its core is the regulated loading of the Mcm2-7 protein complex onto origins of replication exactly once per cell …
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Μελέτη της έκφρασης δεικτών του κυτταρικού κύκλου καθώς και αγγειογενετικών παραγόντων σε ασθενείς με ηπατοκυτταρικό καρκίνωμα, οι οποίοι υπέστησαν μερική ηπατεκτομή για θεραπευτικούς λόγους. Συσχέτιση με την μετεγχειρητική επιβίωση των ασθενών και τους κλασσικούς προγνωστικούς δείκτες της νόσου
… ηπατοκυττάρου. Σε μοριακό επίπεδο, οι βλάβες του DNA, οι γενετικές αλλαγές και η αστάθεια του γονιδιώματος αποτελούν κοινά χαρακτηριστικά της νόσου. Όπως σε όλες τις νεοπλασίες, έτσι και στο ΗΚΚ, κατά την κακοήθη εξαλλαγή τα καρκινικά κύττταρα αποκτούν ορισμένα ιδιαίτερα χαρακτηριστικά όπως ο …