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Showing 1 to 3 of 3 for “"DNA repair kinetics"”.
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Nucleobase deamination as a biomarker of inflammatory processes
… meaning of these increases awaits studies of DNA repair kinetics. dO was not detected in any study at levels above 5 per 10⁸ nt, leading to the prediction that it will not be present at significant levels in inflamed tissues in humans. As a complement to the LC-MS method for the quantification …
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Toxic effects on model mammalian cells by monohalogenated disinfection byproducts: haloacetic acids and haloacetonitriles
… DBPs to make comparisons in terms of genomic DNA damage induction, repair efficiency of induced DNA lesions, and cell cycle alteration using Chinese hamster ovary (CHO) cells as a model mammalian cell system. Both HAAs and HANs are alkylating agents with a halogen atom attached on their carbon …
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Engineering a single cell microarray platform for high throughput DNA damage and repair analysis
DNA damage contributes to cancer, aging, and heritable diseases. Ironically, DNA damaging agents are also commonly used in current cancer treatment. We therefore need robust, high throughput, and inexpensive tools for objective, quantitative DNA damage analysis. The single cell gel electrophoresis …