Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"DNA persistence"”.
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DNA Persistence and Preservation Following Environmental Insult
… such as plane crashes or natural disasters. DNA degradation was assessed in two model organisms, pig and rabbit (with human DNA as a control), over various time points. Rabbit recombination activating gene (RAG 1) was aligned to identify conserved regions in pig, rabbit and human. Primers …
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Human impact on the McMurdo Dry Valley soils of Antarctica: Extending the limits of DNA detection
… research quantified human impact, in the form of DNA released from humans and human-associated microbiota, across spatial and temporal scales. This project was part of the MBIE grant entitled “Evidence-based Risk Assessment of the McMurdo Dry Valley Ecosystem”. Areas of human activity, including …
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Unexpected mechanical properties of nucleic acids
… in many biological life processes. The bending persistence length of DNA is of specific interest, because so much eukaryotic DNA that stores genetic information is tightly packed inside cell nuclei, even though DNA is considered to be a relatively stiff biopolymer. However, recent experiments …
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Methods for Improving Challenging DNA Profiles and Molecular Preservation of Soft Tissue Samples
Degradation of DNA can lead to either poor quality, imbalanced, or even no profiles. Therefore, appropriate collection and storage methods are critical to minimize its impact. If the DNA is degraded prior to sample collection, then the degradation process can only be arrested and other methods have …
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Deformability and Dynamics in Linear and Looped/Supercoiled DNA with Implications for Damage Sensing
… must scan billions of base pairs (bp) of genomic DNA to identify damaged sites and initiate repair. These proteins diffuse rapidly along DNA, with <500 µs “dwell” time per site, while damage recognition—often involving DNA bending or unwinding—occurs over much slower timescales (>10 ms). This …
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Evaluating the efficiency of laundry sanitizers on the removal and transfer of DNA in a washing machine
DNA persistence and transfer has been a topic of much research and study over the last several years in the forensic science field. One interesting subfield that has been investigated is the field of laundered fabrics. It has been discovered that DNA is recoverable from laundered fabrics. The …
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Investigation of the Effects of Environmental Insults on Presumptive and Confirmatory Tests and DNA Degradation
… compromising the quality of the samples and the DNA profiles generated. This problem can be exacerbated when the environmental conditions are harsh. It is widely understood that environmental insults affect the efficacy of presumptive and confirmatory tests and can have a direct impact on the …