Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"DNA origami"”.
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DNA Origami Mechanisms and Machines
This thesis establishes scaffolded DNA origami as a viable approach to designing and fabricating nanoscale mechanisms and machines. The work presented shows a fundamental proof-of-concept for the fabrication of DNA Origami Mechanisms and Machines (DOMM). The scope of the project is to design, …
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DNA Origami-Templated Synthesis of Semiconducting Polythiophene Filaments
… effizient erwiesen. In dieser Arbeit wurde die DNA-Origami-Technik genutzt, um eine funktionale Nanostruktur für elektronische Schaltkreise oder optische Anwendungen zu assemblieren. Planare DNA-Origami-Strukturen können als molekulare Steckbretter dienen, um funktionale Objekte mit …
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Monte Carlo simulation of DNA origami self-assembly
The optimal design of DNA origami systems that assemble rapidly and robustly is hampered by the lack of a model capable of simulating the self-assembly process that is sufficiently detailed yet computationally tractable. In this thesis, we propose a model for DNA origami that strikes a balance …
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Therapeutic applications of DNA origami-based programmable nanoparticles
DNA origami utilizes the complementary Watson and Crick base pairing of DNA to self-assemble highly programmable nanoparticles. These nanoparticles have distinct advantages over other nanoparticle delivery platforms, including polymeric and lipid nanoparticles, in that they offer precise nanoscale …
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Sequence design principles for 3D wireframe DNA origami
DNA is a highly programmable molecule that can be designed to self-assemble into nearly arbitrary 2D and 3D nanoscale structures. DNA origami is a particularly versatile method to achieve complex molecular architectures. However, the rules for designing scaffolded DNA origami have not been …
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Förster resonance energy transfer (FRET)-based nanophotonics using DNA origami structures
… various nanostructures can be produced. Here, DNA nanotechnology and especially the DNA origami technique are auspicious self-assembling methods. By using DNA origami nanostructures different fluorophores can be introduced with a high local control to create a variety of nanoscale photonic …
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DNA Origami Structures for Artificial Light-Harvesting and Optical Voltage Sensing
In the past decade, DNA origami self-assembly has been widely applied for creating customised nanostructures with base-pair precision. In this technique, the unique chemical addressability of DNA can be harnessed to create programmable architectures, using components ranging from dye or protein …
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DNA origami substrates as a versatile tool for surface-enhanced Raman scattering (SERS)
… the highest signal amplification. The use of DNA origami substrates provides both, the arrangement of AuNPs with nm precision as well as the ability to bind analyte molecules at predefined positions. Consequently, the present cumulative doctoral thesis aims at the development of a novel SERS …
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A study of protein-DNA interactions using atomic force microscopy and DNA origami
… by recognising specific sites on the viral DNA and cutting invading viruses at those sites. We aim first to understand how these proteins translocate along the viral DNA molecules toward their recognition sites, and then to see how their accuracy of cleavage can be increased. Protein …
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Direct Single Molecule Imaging of Enhanced Diffusion for Enzymes and Enzyme-conjugated Dna origami
… programmable self-propelled enzyme-powered DNA origami active particles and study the mechanism of propulsion from the bottom-up.</p>
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Development of a Hybrid Carrier System based on DNA Origami Nanostructures and Layer-by-Layer Microcarriers
… Dissertation untersuchte die Kombination von DNA-Nanostrukturen, so- genannte DNA-Origami-Strukturen, mit Layer-by-Layer (LbL) Mikrotransportern zum Auf- bau eines verbesserten Medikamententrägersystems. Dies sollte die jeweiligen Vorteile der eigenständigen Systeme kombinieren um individuelle …
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Development of intelligent stimuli-responsive biomaterials and nanodevices
<p>"Structural DNA nanotechnology utilizes DNA molecules as building blocks to fabricate ordered artificial nanostructures at the molecular level. Among all DNA-based techniques, DNA origami has been considered as one of the most powerful tools for constructing artificial nanostructures with …
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Understanding the Role of Anisotropy on the Optoelectronic and Colloidal Properties of Quantum Rods for Programmable Self-Assembly with DNA Origami
… properties of quantum rods, as well as using DNA-mediated self-assembly to align these quantum rods on DNA origami for energy transfer applications in biocompatible systems. First, CdSe of systematically varied aspect ratios and emission colors, as well as core/shell CdSe/CdS of different …
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Molecular mechanics of DNA bricks: in situ structure, mechanical properties and ionic conductivity
The DNA bricks method exploits self-assembly of short DNA fragments to produce custom three-dimensional objects with subnanometer precision. In contrast to DNA origami, the DNA brick method permits a variety of different structures to be realized using the same library of DNA strands. As a …
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Electronic characterization of solution-synthesized graphene nanoribbons using scanning tunneling microscopy
… as the building blocks towards combining DNA origami and GNR precursors. Finally, a method is proposed to fabricate organized GNRs by attaching GNR precursors to ssDNA to make DNA origami.
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Transport properties of DNA nanostructures
Besides the role of genetic information storage, DNA has been proposed as a new material in nanotechnology. The idea came from the nature-occurring Holliday junction (HJ) which allows more than 2 DNA strands to be assembled. Multiple HJs can be combined with desired orientation to form complex 2- …
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Designing 3D Wireframe DNA Nanoparticles for Programmable Innate Immune Activation
DNA nanotechnology harnesses the predictability and specificity of canonical base pairing interactions to enable the synthesis of complex DNA nanodevices capable of interacting with their environment in a controllable manner. Wireframe DNA origami are a class of highly customizable DNA …
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