Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"DNA microarray analysis"”.
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SNP auto-calling using artificial neural networks
… germane to making progress in the refinement of DNA microarray analysis and techniques regarding this issue. This study attempts to deal with the classification of microarray data and the comparison and validation of simple feedforward ANNs in partitioning high dimensional data. In doing this the …
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SNAP Biclustering
… well in many problem domains, particularly DNA microarray analysis and collaborative filtering. A motivation for this work has been the biclustering technique known as bicACO, which was the first to use ant colony optimization. As bicACO is time intensive, much emphasis was placed on …
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The roles of hepatocyte growth factor family members in androgen-regulation of human hair growth. A comparison of the expression of hepatocyte growth factor family members, HGF and MSP, and their receptors, c-Met and RON, in isolated hair follicles from normal and androgenetic alopecia (balding) scalp.
… chain reaction (RT-PCR), quantitative PCR and DNA microarray analysis), cell culture and immunohistochemistry. Scalp follicles expressed a range of paracrine messenger genes. The dermal papilla, cultured dermal papilla cells and dermal sheath expressed several HGF family genes, while matrix …
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An improved directed random walk framework for cancer classification using gene expression data
… of different fields. Deoxyribonucleic acid (DNA) microarray analysis is one of the modern cancer diagnosis techniques used by scientists to measure the gene expression level changes in gene expression data. From the perspective of computing, an algorithm is developed to ease the diagnosis …
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Integrative analysis of high-throughput biological data: shrinkage correlation coefficient and comparative expression analysis
… exploits the similarity between the replicated microarray experimental samples. The methodology considers both the number of replicates and the variance within each experimental group in clustering expression data, and provides a robust statistical estimation of the error of replicated …
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Immunohistochemical Evaluation and Gene Expression Profiling of Senile Lentigo
… Wnt-5a, p16 and p53 and computer-assisted image analysis were performed. DNA microarray analysis was carried in one female volunteer with both lentigo and melasma. RESULTS: Histological features of senile lentigo of the face were characterized by epidermal hyperpigmentation due to melanocytic …
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CoryneRegNet : a reference database and analysis platform for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions and global DNA microarray hybridization …
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Mutational analysis of the West Nile Virus NS4B protein
… project used protein modeling and phylogenetic analysis of the NY99 WNV NS4B protein in comparison to NS4B proteins from other flavivirus and WNV strains to identify amino acid residues with a theoretical probability of contributing to the function of NS4B. The second aim utilized site-directed …
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Identification and molecular characterization of a putative heme ABC transporter in Neisseria meningitidis
… components of ABC transporters. Using DNA microarray analysis, we identified eleven ABC transporter components. A mutation in one of these genes, the ATPase NMB1993, was constructed. No difference in the ability of various iron sources to support the growth of the mutant and wild-type …
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Transcriptional Regulatory Mechanisms of Ribosomal Protein Genes
… expression of the ribosomal protein genes. DNA microarray analysis has implicated the role of 26S proteasome in transcriptional regulation of the ribosomal protein genes tying protein degradation to protein synthesis pathway. To determine the mechanism as to how the 26S proteasome promotes …
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Controls Over S-Phase And Over Nuclear Synchrony
… and live cell fluorescence microscopy) and DNA microarray analysis. Depletion of the mitotic cyclin induces periodic S-phases correlated with G1/S gene expression, cell volume doubling, and uses mostly mitotic S-phase origins to replicate the genome evenly. We conclude that cyclin dependent …
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Molecular Basis of Calcicole-Calcifuge Physiology.
… morphology of these ecotypes was measured. Also, DNA microarray analysis was utilized to detect genes that are regulated by Ca2+. A differed pattern in the root growth was observed in all the ecotypes at varied external Ca2+ application ranging from 0 mM to 30 mM. The primary root structure and …
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Molecular Mechanisms of Interleukin-1beta-Stimulated Regulation of Angiogenesis in Cardiac Microvascular Endothelial Cells.
… implications in the processes of angiogenesis. DNA microarray analysis indicated IL-1β modulates the expression of numerous angiogenesis-related genes, notably upregulating MMP-2 and downregulating VEGF-D expression. RT-PCR and Western blot analyses confirmed the differential expression in …
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Regulation of Murine Mast Cell Homeostasis by TGF-β1 and CD4+CD25+C Regulatory T Cells
… which mast cells develop was examined through DNA microarray analysis. Wild type (WT) bone marrow cells were stimulated with IL-3+SCF+vehicle or IL-3+SCF+TGF-βI for 10 days and their transcriptomes* analyzed. The results identified which components of transcriptional regulation were regulated …
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Electrochemical Control of Bacterial Persister Cells
… dispersive spectroscopy (SEM-EDS) analysis. Moreover, electrochemical treatments mediated via carbon electrodes provoked the permeabilization of the cells to extracellular materials, and increased their susceptibility to antibiotics, which led to complete eradication of the …
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Optimization of cDNA microarray image analysis methods
… mechanisms that control these changes. With the DNA microarray technology researchers are now able to determine, in a single experiment, the gene expression profiles of hundreds to tens of thousands of genes in tissue, tumors, cells or biological fluids. Accordingly, and since the patterns of …
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New Mediators and Novel Mechanisms in Allergic Airway Inflammation
… seen in the epithelium and in seromucous glands. DNA microarray analysis demonstrated increased levels of S100A7 in nasal lavage fluid cells obtained from patients with allergic rhinitis, both during season and following nasal allergen provocation. These results were confirmed in nasal biopsies …