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Showing 1 to 2 of 2 for “"DNA methylation maintenance"”.
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INVESTIGATING THE LINK BETWEEN HOMOLOGOUS RECOMBINATION PROTEIN BRCA2 AND DNA METHYLATION
… mutation patterns that subvert genome stability. DNA repair and damage response mechanisms are responsible for maintaining stability in normal cells. One such repair mechanism involves homologous recombination (HR) proteins BRCA2 which protects DNA replication intermediates from nuclease-mediated …
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Regulation of De Novo and Maintenance Dna Methylation By Dnmt3A and Dnmt3B
<p>DNA methylation (5-methylcytosine, 5mC) is essential for the regulation of gene expression and integrity of the mammalian genome. It occurs predominantly in the context of CpG dinucleotides to form a symmetrical pattern on both DNA strands, which allows DNA methylation patterns to be …