Global ETD Search
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Showing 1 to 3 of 3 for “"DNA maintenance"”.
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The Functions of Human Dna2 in Mitochondrial and Nuclear DNA Maintenance
Coordination between DNA replication, DNA repair and cell-cycle progression ensures high fidelity DNA replication thus preventing mutations and DNA rearrangements. Interestingly, in addition to nuclear DNA stability, mitochondrial DNA: mtDNA) integrity is also essential for normal development. The …
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Biochemical analysis of proteins in the telomere maintenance pathway
… designated telomeres. The terminal telomeric DNA consists of tandem repeats of a G-rich motif that is established and maintained by the action of the specialized reverse transcriptase called telomerase. In addition to the function of telomerase, the telomere environment requires an efficient …
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Functions of Human DNA2 and its Protein Partners in DNA End Resection
Living organisms must keep their DNA content intact to assure the integrity of their genomic information. DNA replication and DNA damage repair are the main efforts to accomplish this task. Hence, the failure of these mechanisms could lead to genomic instability and subsequently development of …