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Showing 1 to 6 of 6 for “"DNA ligases"”.

  1. Developing as assay to screen inhibitors for various ATP-dependent ligases

    DNA ligases (EC.6.5.1.1) are key enzymes that catalyze the formation of phosphodiester bonds at single-stranded or double-stranded breaks between adjacent 5’-PO4 and 3’-OH groups of DNA. These enzymes are essential guardians of genomic integrity and have recently been drawing a lot of attention as …

    westminster Repository record for Developing as assay to screen inhibitors for various ATP-dependent ligases (opens in a new tab)

  2. Repair eXtreme - DNA repair proteins from Antarctic extremophiles

    … from Antarctic DV systems may possess unique DNA repair enzymes and pathways that enable their survival in such extreme conditions. Exploring these DNA repair systems may offer valuable insights into microbial survival in extreme environments or even extra-terrestrial settings. To investigate …

    waikato-masters Repository record for Repair eXtreme - DNA repair proteins from Antarctic extremophiles (opens in a new tab)

  3. Analysis and confirmation of the results of a yeast two-hybrid screen carried out to identify proteins that interact with drosophila XRCC2

    <p>Repairing DNA damage is brought about by highly specific proteins that partake in a variety of DNA repair. Two of the most common types of damage are double-strand breaks (DSBs) and interstrand crosslinks. A single DSB or crosslink can potentially kill a cell if it is not repaired~ In human and …

    u-pacific Repository record for Analysis and confirmation of the results of a yeast two-hybrid screen carried out to identify proteins that interact with drosophila XRCC2 (opens in a new tab)

  4. Treatment of nonspecific DNA-protein contacts and application to the excision mechanism of a unique human DNA glycosylase

    lethbridge

  5. Computational investigation of the mechanism of action of DNA glycosylases

    lethbridge

  6. Computational insight into the broad substrate specificity of enzymes that process nucleic acids

    lethbridge