Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"DNA folding"”.
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Investigating mechanisms of genome folding by single-cell Hi-C
… have begun to reveal the hierarchy of mammalian DNA folding from the 10 nm fibre to the intact whole genome. One of the key approaches used is the single-cell Hi-C. My lab and I developed a single-cell Hi-C protocol that combines imaging and Hi-C processing on the same cell, and I tried to …
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Information theoretic and machine learning techniques for emerging genomic data analysis
… biological dataset assaying the propensity of a DNA sequence to form a four-stranded structure called ""G-quadruplex"" (GQ). GQ structures have been proposed to regulate diverse key biological processes including transcription, replication, and translation. I present main factors that lead to GQ …
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ORGANIC AND HYBRID INORGANIC-ORGANIC MATERIALS WITH INTRIGUING EMISSIVE PROPERTIES IN THE SOLID STATE
… as promising ligands for such non-canonical DNA folding.[12] [1] E. Lucenti, A. Forni, C. Botta, L. Carlucci, C. Giannini, D. Marinotto, A. Previtali, S. Righetto, E. Cariati, J. Phys. Chem. Lett. 2017, 8, 1894–1898. [2] E. Lucenti, A. Forni, C. Botta, L. Carlucci, C. Giannini, D. Marinotto, …
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In vitro selection of DNAzymes selective for monovalent metal ions and their development as sensors in living cells and organisms
… genetic information, the recognition function (DNA aptamers), the structural function (DNA origami and DNA nanodevices), and most interestingly, the catalytic function (deoxyribozymes or DNAzymes) of DNAs have been explored since 1990s, which attract widespread interest. DNAzymes, fully …