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Showing 1 to 3 of 3 for “"DNA encapsidation"”.
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Analysis, Optimization and Application of AAV Capsid Assembly using Escherichia coli
… delivery was also studied and strategies for DNA encapsidation were tested. Among 13 known human and nonhuman primate AAV serotypes, AAV serotype 2 (AAV2) is the most studied and AAV serotype 5 (AAV5) is the most genetically divergent serotype. To analyze AAV capsid assembly, AAV2 and AAV5 VP3 …
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Relating the structure of the HSV-1 UL25 DNA packaging protein to its function
… electron microscopic (EM) analysis revealed that DNA-containing capsids as well as A- and B-capsids were present in the nuclei of both ΔUL25MO- and KUL25NS-infected cells. As expected, none of the progeny from ΔUL25MO-infected Vero cells expressing the wt pUL25 formed plaques on non-permissive …
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Structure of the GP16 ATPase from the φ29 dsDNA packaging motor
… bacteriophage φ29 packages double-stranded DNA (dsDNA) into a preformed viral shell, or procapsid, and serves as a model system for studying genome packaging in eukaryotic dsDNA viruses such as poxviruses, herpesviruses and adenoviruses. Encapsidation of bacteriophage φ29 DNA is driven by a …