Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"DNA denaturation"”.
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Transistor-based biosensing: expanding the functionality of field effect transistors
… for sample preparation and manipulation through DNA denaturation and cell lysis. Through application of a 10MHz, AC field between the shorted source-drain and the back-gate of the chip, fringing electric fields located just above the transistor surface are generated. These fringing electric …
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Re-evaluation of analytical chemistry techniques in studying DNA structures
… to examine the structural changes that DNA adopts when subjected to a number of external/internal factors. A self-complementary sequence, d(CG)9, and a non-self-complementary sequence (mixed sequence) were used to study the conformational effects displayed by each type of oligonucleotide …
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Towards the development of fluorescent probes targeting aldehyde dehydrogenase (ALDH) in cancer. Expression and epigenetic modulation of ALDH1A1, ALDH2 and ALDH3A1 in selected in vitro models.
… assessed in A549 and U-2 OS cell lines. Thermal DNA denaturation and chemosensitivity assays were used to obtain information about DNA binding properties and cytotoxicity of AAQs and HAAQ congeners. All compounds were shown to be weak*to*moderately binding to DNA, and symmetrical …
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Towards the development of fluorescent probes targeting aldehyde dehydrogenase (ALDH) in cancer. Expression and epigenetic modulation of ALDH1A1, ALDH2 and ALDH3A1 in selected in vitro models.
… assessed in A549 and U-2 OS cell lines. Thermal DNA denaturation and chemosensitivity assays were used to obtain information about DNA binding properties and cytotoxicity of AAQs and HAAQ congeners. All compounds were shown to be weak*to*moderately binding to DNA, and symmetrical …
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Nanoparticle Biofunctionalization for Self-Assembly and Energy Transfer Applications
… quantum dots (QDs), and quantum rods (QRs) with DNA and proteins for self-assembly, energy transfer and drug delivery applications.</p> <p>In the first project, we explored the ability to assemble QDs into clusters with a high degree of control through DNA-mediated interactions. The hydrophobic …