Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"DNA demethylase"”.
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Tet1: A Unique Dna Demethylase For Maintenance of Dna Methylation Pattern
<p>DNA methylation at the C5 position of cytosine (5-methylcytosine, 5mC) is a crucial epigenetic modification of the genome and has been implicated in numerous cellular processes in mammals, including embryonic development, transcription, X chromosome inactivation, genomic imprinting and chromatin …
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Regulation of Active DNA Demethylation and its Role in Fertility in Arabidopsis thaliana
… the lifetime of the plant. Expression of the DNA demethylase REPRESSOR OF SILENCING1 (ROS1) is dependent upon this balance as well as perpetuating it, yet many aspects of the regulation of ROS1 remain unknown. In this work, I show that the downregulation of ROS1 in mutants of the RNA-directed …
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The Epigenetic Role of EGR1 during Postnatal Mammalian Brain Development
DNA methylation is an epigenetic mechanism critical for tissue development, cell specification and cellular function. Mammalian brains consist of millions to billions of neurons and glial cells that can be subdivided into many distinct types of cells. We hypothesize that brain methylomes are …
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Identification and characterization of factors involved in DNA demethylation and anti-silencing in Arabidopsis
<p>DNA methylation is a key epigenetic mark for transcriptional gene silencing in many eukaryotes. DNA methylation status can be dynamically controlled by methylation and active demethylation processes. Compared to the well-known mechanisms of DNA methylation, the mechanisms of DNA demethylation …