Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"DNA damage repair response"”.
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Study of the DNA Damage Complexes Within the HTLV-1 Tax Oncoprotein Interactome
… instability via repression of the cellular DNA damage repair response. Our laboratory has previously shown that the interaction between Tax and various proteins involved in the DNA-damage response pathway impairs the ability of these proteins to mount an efficient repair response. As part of …
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Interplay between an integrative and conjugative element and its bacterial host
… gene transfer, introducing large fragments of DNA. Often, MGEs contain cargo genes beneficial to the host, conferring new traits such as antibiotic resistances, pathogenicity, and metabolic capabilities. Though MGEs sometimes carry beneficial genes, they can impose fitness costs on their host. …
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Cellular interactions of the cytolethal distending toxins
… toxins whose actions upon eukaryotic cells cause DNA-damage, resulting in the induction of DNA-damage repair response, thus leading to the modulation of host cell functions. Most CDTs are hetero-tripartite assemblies of CdtA, CdtB, and CdtC, with CdtB required for CDT-mediated cell cycle arrest, …
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Novel roles of microtubule-associated tau in radiation-induced brain injury
<p>Injury responses in cells lacking proliferation capacity such as terminally differentiated neurons consists of complex mechanisms to ensure cellular homeostasis. Brain tumor patients undergoing radiation therapy experience cognitive impairments similar to those seen in patients suffering from …