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Showing 1 to 4 of 4 for “"DNA cytosine methylation"”.

  1. Genomics and regulatory functions of microRNAs and small silencing RNAs in Arabidopsis thaliana

    … including the miR823-directed cleavage of the DNA cytosine methylation factor CHROMOMETHYLASE3. We also identified a trans-acting siRNA-generating locus which we called TAS4, and confirmed that miR828 triggers phased siRNA production by specifying targeted cleavage of TAS4 transcripts.

    mit Repository record for Genomics and regulatory functions of microRNAs and small silencing RNAs in Arabidopsis thaliana (opens in a new tab)

  2. Synthetic approaches to the understanding of DNA nucleobase methylation

    DNA methylation is a major source of genetic variation and cancer. Methylation occurs when nucleophilic DNA bases react with methylating agent methyl methanesulfonate (MMS), dimethyl sulfate (DMS), N-methyl-N-nitrosourea (MNU), N-methyl-N-nitro-N-nitrosoguanidine (MNNG), etc. …

    njit Repository record for Synthetic approaches to the understanding of DNA nucleobase methylation (opens in a new tab)

  3. Regulation of De Novo and Maintenance Dna Methylation By Dnmt3A and Dnmt3B

    <p>DNA methylation (5-methylcytosine, 5mC) is essential for the regulation of gene expression and integrity of the mammalian genome. It occurs predominantly in the context of CpG dinucleotides to form a symmetrical pattern on both DNA strands, which allows DNA methylation patterns to be …

    uthsc Repository record for Regulation of De Novo and Maintenance Dna Methylation By Dnmt3A and Dnmt3B (opens in a new tab)