Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"DNA catalysts"”.
-
DNA catalysts as phosphatases and as phosphoserine lyases
… that have catalytic roles in nature, whereas DNA is primarily considered to store and transfer genetic information. However, artificial single-stranded DNA has been identified by in vitro selection to catalyze several chemical reactions and several of those are of biological relevance. For in …
-
DNA catalysts for amide bond cleavage and for lysine side chain modification
… however, have been discovered that are made of DNA. One can think of both RNA and proteins as large biopolymers with the potential to form complex secondary and tertiary structures capable of doing catalysis. Given the structural similarities between RNA and DNA, it is reasonable to think that …
-
Kinase deoxyribozymes
… the use of proteins and RNA as enzymes, while DNA is used for the storage and transfer of genetic information. Proteins and RNA are biopolymers that can fold into specific secondary and tertiary structures to enable catalysis. Considering the structural similarity to RNA, single-stranded DNA …
-
Catalysis by DNA enzymes: roles of lanthanide(III) ions and DNA aptamer modules
For many years scientists considered DNA and RNA to be merely the means for the storage and transmission of genetic information. Catalytic roles of some RNA molecules, called ribozymes, were discovered in the early 1980s. Considering structural similarities between RNA and DNA, it was reasonable to …
-
ENZYME-LIKE DNA CATALYST DESIGN
This work develops DNA as a programmable chiral platform for asymmetric catalysis in water. It first reviews the promise and limitations of DNA-based catalysis: although DNA offers chirality, structural programmability, aqueous compatibility, and sustainability, existing systems are often limited …
-
DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates
… a close analog of RNA, the catalytic ability of DNA was evaluated and the first artificial DNA catalyst (deoxyribozyme) discovered in 1994. Since then, deoxyribozymes have been shown to catalyze a wide variety of chemical reactions, including phosphodiester bond cleavage, nucleic acid ligation, …