Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"DNA arrays"”.
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Fingerprinting and characterisation of Escherichia coli isolates using DNA arrays
Two commercially available DNA whole genome Escherichia coli K12 arrays were compared to identify a subset of markers for typing. The arrays were identical in probe composition but different in substrate (membrane and glass slide arrays) and probe preparation (radio- and fluorescent-labelled). …
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Functional Genome Analysis of Mycobacterium tuberculosis
Anhand filterbasierter DNA-Arrays, die sämtliche offenen Leseraster von Mycobacterium tuberculosis repräsentieren, wurde eine funktionelle Genom-Analyse des Erregers der Tuberkulose durch geführt. Ein Genom-Vergleich von Mitgliedern des M. tuberculosis-Komplexes wies zusätzlich zu den bekannten …
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Extending the realm of SuNS to DNA nanoarrays and peptide features
Intense research on DNA arrays has been fostered by their applications in the field of biomedicine. DNA microarrays are composed of several different DNA sequences to be analyzed in parallel allowing high throughput information. Current methods to fabricate these arrays are serial in nature …
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Linking genetic regulation and the metabolic state
… throughput, effort, and cost compared with DNA arrays. Our sample workup method enables simultaneous metabolite measurements with coverage throughout central carbon metabolism and amino acid biosynthesis, using a standard Gas Chromatography Mass Spectrometry (GC-MS) platform optimized for …
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Utilizzo della tecnologia microchip per l'identificazione di geni candidati responsabili dell'aumento di HbF.
… mutation and lack adult b globin. Genome-wide DNA arrays were run on 14 TD and 14 NTD patients using the Affymetrix 500K (500,568 SNPs) SNP chip platforms. The average sample cali rates were 94.3% for the 500K chip. Additional samples are being analyzed in an attempt to achieve sufficient power …
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Neue DNA-Biosensoren mit direkter elektrochemischer Detektion auf Basis von Metall-PNA-Konjugaten
… die Entwicklung neuartiger Biosensoren für die DNA-Analytik auf der Basis von Konjugaten aus Peptid-Nukleinsäure(PNA) mit kovalent gebundenen Metallocenen (Ferrocen und Cobaltocenium) beschrieben. Kommerziell erhältliche DNA-Arrays sind hinsichtlich der Erkennung von Punktmutationen in den …
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Untersuchungen zur Genomstruktur und Biofilmbildung von pathogenen Escherichia coli Isolaten
… wurde im Rahmen dieser Arbeit ein spezieller DNA-Array entwickelt. Dieser enthielt zahlreiche Sonden für Gene, die für die Virulenz von verschiedenen Erregern der Gattung E. coli als auch der Untergruppe Shigella charakteristisch sind. Mit diesem "Pathoarray" wurde die Verbreitung von …
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Volatile Organic Compound Detection And Disease Diagnostics Using Dna-Functionalized Carbon Nanotube Sensor Arrays
… nose” (e-nose) platform based on chemical sensor arrays capable of detecting and differentiating between various VOCs of interest. Sensor arrays were fabricated in a field-effect transistor (FET) configuration with exquisitely sensitive carbon nanotubes (CNTs) as the channel material. The …
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Herstellung und Validierung von Tissue Microarrays von Knochenmarkbiopsien
Today, the construction of tissue microarrays in order to investigate the expression of proteins and genes on large case series is an approved and accepted method. The applicability of the tissue microarray technique for analysis of bone marrow biopsies has not been tested before and up to now not …
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Studies on the Role of Histone-like Proteins in Gene Regulation in Uropathogenic Escherichia coli Isolate 536
… of virulence-associated genes by using DNA arrays and classical phenotypic assays, most of the observed effects were mediated by the H-NS protein alone. Expression profiling revealed that transcript level of more than 500 genes was affected by an hns mutation, resulting in increased …
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Λειτουργική και γονιδιωματική ανάλυση της επίδρασης αναλόγων του ρετινοϊκού οξέος σε ανθρώπινα κερατινοκύτταρα
Τα ρετινοειδή αποτελούν μια σημαντική κατηγορία μορίων που επηρεάζουν ποικίλες βιολογικές διαδικασίες, όπως τη διαφοροποίηση των επιθηλιακών και μη-επιθηλιακών ιστών, την απόπτωση και τη ρύθμιση του κυτταρικού κύκλου. Επίσης, σημαντικός είναι ο ρόλος τους στην όραση, την ανάπτυξη και την …