Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"DNA Evolution"”.
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Exploring the origins of DNA using synthetic biology Alannah Marie
The extreme conservation of DNA makes it difficult to trace the deep evolution of this fundamental molecule. The precursors of DNA are produced from the constituent RNA precursors through ribonucleotide reduction, leading to the logical conclusion that DNA evolved after RNA. Thymine (T) is produced …
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Creating sense from non-sense DNA: de novo genesis and evolutionary history of antifreeze glycoprotein gene in northern cod fishes (gadidae)
… of the gadid phylogeny, indicating a complicated evolutionary history of AFGP in the gadid lineage. The AFGP loci in three gadid species were isolated and characterized to investigate the genetic origin and evolutionary pathway of the AFGP gene family in the gadid lineage. Two of these species are …
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Directed evolution of an HIV-1 LTR specific recombinase for anti-retroviral therapy- a proof of concept study
The prospect of the work presented in this thesis has been to engineer Cre recombinase to recognize and recombine a sequence from an HIV-1 Long Terminal Repeat (LTR), characterize the recombination proficiency of the evolved recombinase in mammalian cells and explore the potential of the …
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Duplication is a prominent mechanism of recent gene birth in Caenorhabditis elegans
… of gene birth mechanisms that act over a long evolutionary timescale. However, the lack of several reference-quality genomes for different individuals of the same species has hampered the study of the mechanisms of more evolutionarily young gene births. Despite the high throughput brought about …