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Showing 1 to 1 of 1 for “"DNA Breaks, Double-Stranded"”.
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Targeting DNA Double-Strand Break Repair to Potentiate Radio- and Chemo Therapy of Glioblastoma
… was due to the augmented repair of TMZ-induced DNA double strand breaks (DSBs). TMZ induces DNA replication-associated DSBs that are repaired primarily by the homologous recombination (HR) pathway. We found that cell lines from recurrent cultures exhibited faster resolution of Rad51 foci and …