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Showing 1 to 1 of 1 for “"DNA -- Synthesis; DNA -- Biosynthesis; Glycoproteins; DNA Polymerases;"”.
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The Impact of Nucleoside Sugar Modification on Biochemical DNA Transactions
Discrimination by DNA polymerases controls the fidelity of DNA replication, and reduced fidelity results in mutations essential in the etiology of cancer. Polymerase discrimination operates at both dNTP insertion and subsequent elongation steps, and involves several energetic and structural factors …