Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 61 for “"DMN"”.
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The cognitive function of the DMN and its role in consciousness
… (ICNs). Among them, the default mode network (DMN) has generated substantial interest and discussion for its distinct features and function. Accumulating empirical evidence from healthy participants and clinical cohorts suggests that the spatiotemporal integrity of the DMN is important for …
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Vascular Risk, Functional Connectivity, and Episodic Memory in Older Adults
… functional network, the "default mode network" (DMN), is thought to subserve self-referential thought and autobiographical memory. DMN regions include the ventromedial prefrontal cortex, inferior parietal lobe, hippocampus, and the primary "hub" of this network, the posterior cingulate cortex …
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Investigating default mode network activation during external task switches and movie watching
The Default Mode Network (DMN), typically associated with internally-directed thought, shows increased activity during demanding external task switches between cognitive domains, as reported by Crittenden et al. (2015) and Smith et al. (2018), which challenges prevailing views of DMN function. What …
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The inefficiency of open-loop fMRI experiments
The default mode network (DMN) is a highly cited neural network whose functional roles are not well understood. Until recently, event related fMRI experiments used to study the DMN could only be conducted in an open-loop format. The purpose of this study was to demonstrate the potential statistical …
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Analysis of the potato sprout inhibitor 1, 4-dimethylnapthalene: HPLC method development and applications.
1,4-Dimethylnaphthalene (1,4-DMN) is a pesticide used for inhibiting the sprouting of stored potatoes, and therefore prolonging the storage time. It is registered for commercial use in different parts of the world (e.g. USA and New Zealand) and its registration process in the EU is at an advanced …
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Neural Mechanisms Supporting Default Mode Network Regulation of Pain Sensitivity
… a possible role for the default mode network (DMN) both in pain and pain sensitivity. The present thesis aimed to determine the underlying neural mechanisms of DMN involvement in pain and whether the DMN contributes to inter-individual differences in pain sensitivity. Relationships between pain …
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A functional imaging study of the relationship between the Default Mode Network and other control networks in the human brain
The Default Mode Network (DMN) is a large-scale brain network implicated in the control and monitoring of internal modes of cognition. The aim of this research was to investigate DMN function and its relationship to other large-scale cognitive control networks through functional connectivity …
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Structural and Functional Properties of Social Brain Networks in Autism and Social Anxiety
The default mode network (DMN) is active in the absence of task demands and during self-referential thought. Considerable evidence suggests that the DMN is involved in normative aspects of social cognition, and as such, disruptions in the function of DMN would be expected in disorders characterized …
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The role of the default mode network in contextual control
… studies of contextual control do not implicate DMN regions by comparing context-dependent decision making using rich, meaningful scenes, in comparison to arbitrary letter stimuli. DMN regions of the posterior cingulate cortex, parahippocampus and posterior inferior parietal cortex are found to …
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Test-retest Reliability of Intrinsic Human Brain Default-Mode fMRI Connectivity: Slice Acquisition and Physiological Noise Correction Effects
… we use the test-retest reproducibility of the DMN. The guiding hypothesis is that methods that improve reproducibility should reflect more efficient corrections and thus be preferable in longitudinal studies. The physiological denoising study evaluated longitudinal changes in a 3T harmonized …
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Factors Affecting Resting-State Functional Connectivity Across Three Intrinsically Connected Networks in Traumatic Brain Injury
… connected networks; the default mode network (DMN), central executive network (CEN), and salience network (SN). The aim was to develop a predictive model for each network, based off a combination of cognitive performance, brain volumetric factors, aging/demographic factors, and TBI-related …
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Associations Between Resting State Functional Connectivity and Trajectories of General Psychopathology in Emerging Adolescents
… altered connectivity of the default mode (DMN), frontoparietal (FPN), salience (SN), ventral and dorsal attention (VAN and DAN), and cingulo-opercular (CON) networks were associated with between-person differences and within-person rates of change of p-factor scores over three years. …
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Representational dynamics across multiple timescales in human cortical networks
… demand (MD) network, and default mode network (DMN). Chapter 1 provides a background review of the current literature. It begins by reviewing experimental investigations of component visual processes that unfold over time. Next, the MD network is introduced as a collection of frontal and …
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Intrinsic Biophysical Properties of Frog Central Auditory Neurons
… auditory centers, the dorsal medullary nucleus (DMN), the torus semicircularis (TS), and the auditory thalamus. In the second chapter, I showed that the membrane properties of DMN neurons are heterogeneous---they show diverse biophysical phenotypes (which can be characterized by the different …
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Early neighborhood disadvantage and risk for internalizing problems: underlying neurobiological mechanisms
… in the central executive (CEN), default mode (DMN), and salience networks (SN) were computed. Hair cortisol concentration (HCC) and perceived stress were measured for the full sample. For a subsample (N = 40), resting heart rate variability (HRV) was measured in a separate session after the MRI …
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Effects of bipolar disorder on intrinsic brain networks
… networks (IBN), like the default mode network (DMN) and executive control network (ECN), which are consistent with previously established functional and anatomical relationships within the brain. Analysing the functional connectivity (integrity, extent and inter-relationships) of these networks, …
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Functional Localization of Brain Activity in the Iowa Gambling Task Using Graph-Theoretical Methods
… Scaled Inclusivity method localized areas of the DMN across both task states in addition to rest. However, permutation tests of the SI maps revealed significant differences in the spatial extent of DMN consistency across all three tasks. The future application of both methods for functional …
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Development of dissolving and hydrogel-forming microneedles for delivery of vancomycin hydrochloride
… (VCL). VCL was formulated into dissolving MN (DMN), in combination with a variety of different excipients. In an alternate approach, VCL reservoirs, namely film dosage forms, lyophilised wafers and compressed tablets, were integrated with hydrogel-forming MN (HFMN). The physicochemical …
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Where Does it Stem From? - Functional Neuroimaging of Monoaminergic Brainstem Nuclei in Altered States of Consciousness: Translational, Diagnostic and Therapeutic Implications
… networks (such as the default mode network; DMN) whose disintegration is common across both pharmacological transient and pathological chronic ASCs. However, these cortico-centric network accounts have largely been unable to fully characterise fundamental neurobiological processes which may …
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Differences in resting state functional networks in HIV infected and uninfected children at age 7 years
… control, posterior default mode network (pDMN) and default mode network (DMN) . No significant group level differences were found in any RSNs using ICA. However, seed-based correlation analysis ( SCA ) revealed two regions where uninfected children had a higher FC compared to infected …
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