Global ETD Search
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Showing 1 to 20 of 148 for “"DMD"”.
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Novel DMD-based Lidar and Display Systems
Digital Micromirror Devices (DMD) have been used in prescribed optical architectures for decades with very little deviation. These prescribed architectures most commonly include F-number-limited illumination to project a binary spatially-modulated DMD to a distant plane. Rather, this dissertation …
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DMD and POD Modal Analysis for Store Separation
… (POD) and Dynamic Mode Decomposition (DMD). The computational fluid dynamic (CFD) solver Ansys Fluent was employed to obtain flow field data around a representative vehicle and store. Preliminary validation of the numerical results was initially preformed and the results showed good …
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Durability and Longevity of Gene Edited DMD Skeletal Muscle
The content of this work is adapted with or without modifications from the previously published articles that are cited below. Sections that have been reproduced from previously published work have been clearly indicated at the beginning of each section.
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Rekombinationshäufigkeit in Abhängigkeit vom Entbindungsalter der Mütter für das DMD-Gen (Xp 21.2)
… mehrere flankierende und intragene Marker des DMD-Genes bekannt. Um eine Vergleichbarkeit der einzelnen Personen zu erreichen, wurden die Grenzen des zu untersuchenden DNA-Bereiches bei den Markern DYS I,II,III sowie STR 56 gesetzt. Die Frauen wurden anschließend nach dem Entbindungsalter in …
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IMPACT OF DRP1 ACTIVATION, UNFOLDED PROTEIN RESPONSE INDUCTION AND FGF21 LEVELS IN DMD PROGRESSION
Duchenne muscular dystrophy (DMD) is a severe genetic progressive muscle-wasting disease. The transmission of this pathology is X-linked recessive with an incidence of at least 1:5000 newborn boys. Patients typically present the first symptoms related to motor impairments very early in childhood …
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Process modeling for solidification microstructure and transient thermal stresses in laser aided DMD process
… in Laser Aided Direct Material Deposition (DMD) process adverse effects of process parameters on variety of properties and microstructure have been reported. De-bonding at substrate-deposition interface and cracking in deposited layers are a few that occur due to excessive stress build-up. …
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Cognitive profile in advanced Duchenne Muscular Dystrophy (DMD) and the effects of hypoventilation on cognition
The portfolio has three parts.
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Characterization of Cardiomyopathy in a Mouse Model of Duchenne Muscular Dystrophy (DMD) Using Echocardiography, DCE-CT, and PET-FDG
Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disease that is the result of a loss of functional dystrophin, which causes cardiomyocyte fibrosis and death, leading to cardiomyopathy. In this thesis, I have utilized dynamic contrast-enhanced computed tomography (DCE-CT), …
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Reduced order modeling for stochastic prediction and data assimilation onboard autonomous platforms at sea
… We find that Dynamic Mode Decomposition (DMD), a data-driven dimensionality reduction algorithm, can be used for accurate predictions for short periods in ocean environments. We evaluate DMD methods for ocean PE simulations by comparing and testing several schemes including domain …
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Reduced Order Modeling for Stochastic Prediction and Data Assimilation Onboard Autonomous Platforms At Sea
… We find that Dynamic Mode Decomposition (DMD), a data-driven dimensionality reduction algorithm, can be used for accurate predictions for short periods in ocean environments. We evaluate DMD methods for ocean PE simulations by comparing and testing several schemes including domain …
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Optimization of an in vitro model to study Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy (DMD) is the most common inherited muscle disease, affecting 1 out of 5000 male live births. DMD pathology results from genetic and biochemical defects in the dystrophin-glycoprotein complex causing membrane instability, and accordingly, muscle fragility, apoptosis and …
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Effects of mutant SHP2 expression on heart function in Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy that is caused by a mutation in the dystrophin gene which is located on the X chromosome. DMD affect 1 in 3,600 males at birth. Due to recent advancements in treatment of the skeletal muscle disease, patients with DMD have …
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Optimization Methods for Dynamic Mode Decomposition of Nonlinear Partial Differential Equations
… focuses on the dynamic mode decomposition (DMD) applied to nonlinear PDEs with periodic boundary conditions. It provides one study of an existing optimization framework for the DMD method known as the Optimized DMD and provides another study of a newly proposed optimization framework for the …
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Development of a Duchenne Muscular Dystrophy Registry in South Africa to optimise care
… dystrophies is Duchenne Muscular Dystrophy (DMD) and globally, the incidence is 1 in 3500 live male births. Currently, DMD has no cure, the latest care guidelines, especially on corticosteroids, cardiac interventions, and non-invasive ventilation, are all associated with improved muscle …
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Klinische Bedeutung der Kardiomyopathie bei Muskeldystrophie Duchenne und Becker-Kiener
… bei der Muskeldystrophie Duchenne (DMD) und Becker-Kiener (BMD)zu untersuchen. Dazu wurde in der Muskeldystrophie-Ambulanz eine standardisierte Querschnittsuntersuchung (EKG, 24h-EKG, Echo) sowie eine retrospektive Analyse der Krankengeschichte der Patienten durchgeführt. <br>Die …
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Aorta-derived mesoangioblasts for cell therapy of cardiomyopathy in Duchenne Muscular Dystrophy
… are affected. Duchenne muscular dystrophy (DMD) is a fatal muscle-wasting disease, and patients with DMD do not survive beyond their early 30s. The most common causes of the death in DMD patients are cardiac and respiratory failure. Currently, there are advanced treatments and equipment for …
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Prevention of Duchenne Muscular Dystrophy by CRISPR/Cas Therapeutic Genome Editing
… on human health. Duchenne muscular dystrophy (DMD) is a lethal neuromuscular disorder, caused by mutations in the DMD gene on the X chromosome, which consists of 79 exons encoding dystrophin protein. Patients with DMD develop progressive muscle weakness and cardiomyopathy, and ultimately …
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Evaluation of Internal Markers for Predicting Digestibility and Fecal Output by Cattle Fed Bermudagrass Hays of Varying Quality
… lignin (ADL) to predict digestibility (DMD) and fecal output (FO) by cattle fed bermudagrass <em>[Cynodon dactylon </em> (L.) Pers.] hay-diets categorized by their low (L), medium low (ML), medium high (MH), or high (H) CP concentrations (79, 111, 131, and 164 g/kg DM, respectively) was …
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Duchenne muscular dystrophy in South Africa : molecular aspects
… Town, South Africa. Duchenne muscular dystrophy (DMD) is a lethal X-linked neuromuscular disorder, characterised by progressive muscle wasting and weakness. DMD has its onset in early childhood, leading to physical handicap by the mid-teens and usually death by the age of twenty years. Becker …
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Functioning among Taiwanese Families with a Child Having Duchenne Muscular Dystrophy
… with a child having Duchenne Muscular Dystrophy (DMD). This research investigated the level of a child's mobility upon family hardiness, functioning, and support from a family perspective. A total sample of 126 of participants was parents of children with DMD. Parents completed basic demographic …
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