Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"DKD"”.
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Next Generation Sequencing and Genome-Wide Association Studies to Identify Mitochondrial Genomic Features Associated with Diabetic Kidney Disease
Diabetic kidney disease (DKD) affects ~40% of persons with diabetes and is the leading cause of chronic kidney disease and end-stage renal disease globally. Mitochondrial dysfunction is implicated in the pathophysiology of DKD. Previous research reported SNPs in nuclear genes, which influence …
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Phosphodiesterase 1 (PDE1) at the Crossroads of Calcium and Cyclic Nucleotide Signaling in Diabetic Nephropathy
Diabetic Kidney Disease (DKD) is a major complication of diabetes. Incomplete understanding of its molecular mechanisms is highlighted by the limited treatments options. We hypothesized that inhibition of protective endogenous mechanisms plays major role in the pathogenesis of DKD. While …
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The impact of social deprivation on development and progression of diabetic kidney disease
… globally by 2045. Diabetic kidney disease (DKD) develops in up to 40% of people living with diabetes, and significantly increases morbidity and mortality. Social deprivation is well established as a risk factor for poorer health outcomes. Social deprivation is associated with increased …
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Identification and evaluation of novel biomarkers in diabetic kidney disease
Introduction: Diabetic kidney disease (DKD) is a progressive microvascular complication that leads to a decline in renal function and is the most frequent cause of end-stage renal disease. Currently, there is a need for improved biomarkers for the early detection of DKD. microRNAs (miRNAs) are …
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Evaluation of genetic variants for Type 2 diabetes associated kidney disease in African Americans
… million/year) in 2014. Diabetic kidney disease (DKD), primarily attributed to type 2 diabetes (T2D), including ESKD and advanced chronic kidney disease (CKD) accounts for over 40% of all ESKD cases. Observation of familial aggregation in epidemiologic studies suggests that genetic factors may …
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Urinary Biomarkers and Patient Outcome in Chronic Kidney Disease and Atherosclerotic Heart Disease: The value of IgM-uria and IgG-uria
… not all patients with diabetic kidney disease (DKD) have albuminuria. Furthermore, albuminuria is not essentially associated with endothelial dysfunction or glomerular lesions in non-diabetic patients. Urinary excretion of larger proteins, such as IgM and IgG would better reflect glomerular …
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Location based authenticated multi-services group key management for cyber security in high speed broadband wireless multicast communications. Multi-service group key management scheme with location based handover authentication for multi-handoffs participating in multi-group service subscriptions, its performance evaluation and security correctness in high speed broadband wireless multicast communications
… offloaded from the Domain Key Distributor (DKD) to the intermediate cluster controllers, Area Key Distributors (AKDs), in a distributed fashion, using the proposed location based authenticated membership list (SKDL). A significant upgrade of fast handoff performance with reduced performance …
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Predictive Role of NGAL – Neutrophil Gelatinase-Associated Lipocalin as an Early Marker for Renal Injury in Patients with Diabetes Mellitus Type 1 And Type 2 // Предиктивна роля на NGAL – неутрофил гелатиназа асоцииран липокалин като ранен маркер за бъбречно увреждане при пациенти със ЗД тип 1 и ЗД тип 2
Дисертационният труд разглежда ролята на Неутрофил гелатиназа-асоцииран липокалин (NGAL) като маркер за бъбречно увреждане при пациенти със захарен диабет (ЗД). Съществен принос са определените възрастово и полово диференцирани референтни граници на pNGAL, uNGAL и uNGAL/uCreatinine (UNC) за …