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Showing 1 to 1 of 1 for “"DIRAS"”.
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The Role of The Diras Family Members In Regulating Ras Function, Cancer Growth and Autophagy
<p><em>DIRAS3 </em>is a maternally imprinted tumor suppressor gene that is downregulated by multiple mechanisms across several tumor types. When re-expressed, DIRAS3 decreases proliferation, inhibits motility, and induces autophagy and tumor dormancy. <em>DIRAS3</em> encodes a 26 kDa small GTPase …