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Showing 1 to 2 of 2 for “"DHHC proteins"”.
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Enzymology of DHHC-mediated Protein S-Acylation
… is the post-translational modification of proteins with long-chain fatty acids at cysteine residues via a thioester linkage. The most commonly attached lipid is 16-carbon palmitate, thus the process is often called palmitoylation. Unlike other lipid modifications, protein …
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Dhhc5 Regulates Beta-Adrenergic Signaling In The Heart Through Palmitoylation of G Alpha Proteins
… stability. Recent studies have shown that some proteins undergo extremely rapid palmitoylation/depalmitoylation cycles after cellular stimulation supporting a direct signaling role for this posttranslational modification. The work in this dissertation investigated whether β-adrenergic …