Global ETD Search
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Showing 1 to 9 of 9 for “"DHEAS"”.
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DHEA-Substitutionstherapie bei gesunden älteren Männern mit niedrigem DHEAS-Serumspiegel
… sein Sulfatester Dehydroepiandrosteronsulfat (DHEAS) gehören zur Gruppe der adrenalen Androgene und sind wichtige Vorläufersubstanzen der Androgen- und Östrogensynthese beim Menschen. Die adrenale Androgensynthese beim Menschen weist einen Rückgang mit zunehmendem Alter auf. Damit stellt sich …
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Dehydroepiandrosterone and dehydroepiandrosterone sulphotransferase activity and expression in human disease
… (DHEA) and its sulphate ester, DHEAS are the most abundant circulating steroid hormones in humans. Uncongugated DHEA predominately exerts its effects via its downstream conversion to active sex steroids in peripheral target tissues. In contrast the conversion of DHEAS to …
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Selective Lesion of Cholinergic Neurons of the Septal-Hippocampal Tract: Memory and Learning
… sulfatase inhibitors increase whole brain DHEAS levels, enhance ACh release in the hippocampus, and enhance memory. The present study also investigated the cognitive effects of sulfatase inhibition in SAP lesioned animals. Steroid sulfatase inhibition further impaired acquisition of the DMP …
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The Steroid Sulfatase Inhibitor (p-O-Sulfamoyl) - Tetradecanoyl Tyramine (DU-14) Enhances Memory Retention in Passive Avoidance in Rats with Hippocampal Cholinergic Deficit
… such as dehydroepiandrosterone sulfate, (DHEAS) are steroidal compounds synthesized within the central nervous system that modulate its function. Among the effects associated with sulfated neurosteroids is the enhancement of memory. Previous studies have demonstrated that altering the …
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Impact of N-Acetyl-L-Cysteine on the Pathology of Experimental Parkinson’s Disease in Vivo
… neuromodulator dehyroepiandrosterone sulfate (DHEAS), in experimental models of Parkinson’s disease in vivo. To accomplish this goal, we first established multiple animal models of Parkinson’s disease that mimicked oxidative and/or proteotoxic stress: the 6-hydroxydopamine (6-OHDA) model of …
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The relationship of arylsulfatase C and the steroid sulfatases in mammals
… and dehydroepiandrosterone-sulfate sulfatase (DHEAS-sulfatase). They have similar subcellular localization, are membrane bound, have alkaline pH optima, are resistant to inhibition by sulfate and phosphate, and are glycoproteins.
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Descripción de hallazgos clínicos, paraclínicos e histológicos en mujeres con pérdida de pelo de patrón femenino en el servicio de consulta externa Méderi año 2016-2017
… de las pacientes presentaron niveles hormonales DHEAS (dehidroepiandrosterona) y testosterona dentro de límites normales. El 33.3% presentaba niveles bajos o con insuficiencia de vitamina D y ferritina. La TSH estuvo normal en el 66.6% de las pacientes y el 33% reportaba rangos para …
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Pharmakokinetik und Biokonversion von Dehydroepiandrosteron nach Dexamethason-Vorbehandlung bei Frauen mit dem Syndrom der polyzystischen Ovarien
… Zunahme der Serumkonzentrationen für DHEA, DHEAS, Androstendion und Testosteron in der Fläche unter der Konzentrations-Zeit-Kurve. Allerdings waren nach DHEA-Einnahme die Anstiege bei den PCOS-Frauen für 5alpha-Dihydrotestosteron (DHT) (P < 0,01) und dessen Hauptmetaboliten …
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Validation of the obese Ossabaw miniature pig as a model of the obese polycystic ovary syndrome phenotype with concomitant metabolic syndrome: exploration of polycystic ovary syndrome pathophysiology using in vivo and in vitro
… only) and gilts (androstenedione and DHEAS) became hyperandrogenemic; 4) both OSS sows and gilts developed protracted estrous cycle length; 5) both OSS sows and gilts developed increased numbers of medium (3.5-6.5 mm) and large (6.5-12.5 mm) size follicles during the luteal phase of …