Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"DExD/H-Box"”.
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Recombinant DDX58 associates with SOD1 protein and selective miRNA changes in secreted EVs
… we studied a novel EV-associated function for DExD/H-Box Helicase 58 (DDX58) RNA-binding protein, also known as RIG-I (retinoic acid inducible gene I). DDX58 is a cytosolic RNA sensor involved in innate immunity against viruses. Upon viral RNA (as well as host ncRNA) binding, it associates to …
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Structural studies of spliceosome assembly and catalysis
… gave the first structural insight into how the DExD/H-box helicase proteins might remodel ribonucleoprotein complexes. The structure of the spliceosome immediately after exon ligation shows the connected 5′ and 3′ exons and how the active site is remodelled to allow two different reactions in a …
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Kristallstrukturanalyse des spleißosomalen DEAD-Box Proteins hPrp28
DEAD-Box Proteine gehören zur Superfamilie der Helikasen. Sie verwenden die Energie aus der ATP-Hydrolyse, um RNA-RNA- oder RNA-Protein-Interaktionen aufzulösen und katalysieren auf diese Weise Konformationsänderungen in Ribonukleoproteinkomplexen. Das DEAD-Box Protein hPrp28 ist Bestandteil des U5 …