Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"DEC205"”.
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Monocyte Derived Dendritic Cells: Sentinels and Translators of Immune Response to Staphylococcus aureus
… Finally, we identified a unique population of DEC205⁺CD8<sup>a+</sup> in monocyte derived DC. We further elucidated the role of DC DEC205, a C-type lectin, in <i>S. aureus</i> uptake. Blocking of receptor mediated endocytosis resulted in reduced uptake of <i>S. aureus</i> by DC. Confocal …
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Induction of Innate and Adaptive Immunity In Vivo by Selective Antibody Targeting of Poly dA:dT and Antigen to Dendritic Cells
… poly dA:dT, to the DC uptake receptor, DEC205 (DEC). We will show that inoculation of α-DEC-poly dA:dT fusion monoclonal antibodies (mAbs) is sufficient to induce rapid innate cytokine production by DCs. Adaptive T cell immunity is also elicited when the fusion mAb is given in …
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Consequences of Aryl hydrocarbon receptor activation in dendritic cells
… regulatory CD11c<sup>high</sup>CD8á<sup>+</sup>DEC205<sup>+</sup> splenic DCs. Additionally, TCDD increased the expression of CD86 and CD54, while decreasing the frequency of CD11a and MHC II on the splenic CD11c<sup>high</sup> DCs. Although TCDD did not alter the number and frequency of …
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Consequences of Aryl hydrocarbon receptor activation in dendritic cells
… regulatory CD11c<sup>high</sup>CD8á<sup>+</sup>DEC205<sup>+</sup> splenic DCs. Additionally, TCDD increased the expression of CD86 and CD54, while decreasing the frequency of CD11a and MHC II on the splenic CD11c<sup>high</sup> DCs. Although TCDD did not alter the number and frequency of …