Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"DEAD-box protein"”.
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Local and global investigations into DEAD-box protein function
… indeed misfold in the cell; however, chaperone proteins promote escape from these non-native states and foster folding to functional conformations. DEAD-box proteins are ATP-dependent RNA chaperone proteins that function by disrupting structure, which can facilitate structural conversions. Here, …
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The role of human DEAD-box protein DDX3X in the activation and function of Estrogen Receptor-alpha
The human DEAD-box RNA helicase DDX3X was shown to be involved in innate immune signalling pathways mediated by IKKε and TBK1. Interestingly, both DDX3 and IKKɛ have independently been shown to act as breast cancer oncogenes. In breast cancer, DDX3 expression was shown to be upregulated and linked …
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Approach to the identification of sex-determining genes in the tilapia genome by genetic mapping and comparative positional cloning
… Fugu, tilapia, and human. A few genes such as a DEAD box protein, Sox family, and a LIM/homeobox, seem to be good candidates for sex-determining genes, and will need further study. AFLP (amplified fragment length polymorphism)/BSA (Bulked segregant analysis) technique was performed to add more …
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Kristallstrukturanalyse des spleißosomalen DEAD-Box Proteins hPrp28
DEAD-Box Proteine gehören zur Superfamilie der Helikasen. Sie verwenden die Energie aus der ATP-Hydrolyse, um RNA-RNA- oder RNA-Protein-Interaktionen aufzulösen und katalysieren auf diese Weise Konformationsänderungen in Ribonukleoproteinkomplexen. Das DEAD-Box Protein hPrp28 ist Bestandteil des U5 …
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A dynamic transcriptome technique for transcriptional profiling and gene regulatory network involving the helicase antigen (HAGE)
… antigen (HAGE), a cancer/testis (CT) antigen and DEAD-box protein found to be present in numerous types of malignancy. As with the majority of CT antigens, the role of HAGE remains unclear. In this instance, studies were carried to discover the function of HAGE in malignant cells. Preliminary in …
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Characterization of splicing mechanisms by single-molecule fluorescence
… vivo</i>, this process is mainly assisted by protein cofactors. However, the exact mechanism of protein-mediated splicing of group II intron RNA is still not known. </p> <p> In order to elucidate the mechanism of protein-mediated splicing of group II introns, we have studied the folding …