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Showing 1 to 1 of 1 for “"DEAD-box RNA Helicases"”.

  1. Mechanism of Ubiquitin Induced Activation of RIG-I Like Receptors in Antiviral Innate Immunity

    … MDA5, are essential for the detection of viral RNA in the cytoplasm. Upon viral recognition, RIG-I and MDA5 activate the mitochondrial signaling protein AVS, and initiate downstream signaling pathways that activate the transcription factors NF-kappaB and IRF3. These transcription factors …

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