Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"DDX55"”.
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Investigating the polyphosphate interactome with lysine- and histidine-rich proteins
… as well as the ATP-dependent RNA helicase, DDX55. We also studied the non-canonical HPM target protein, histidine-rich glycoprotein (HRG) to which we uncovered that HPM reduced its ability to bind IgG1. Moreover, we demonstrate that S100A9, a known ligand of HRG, is prone to multimerization …
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Polyphosphate Modification of Human Proteins and a New Mechanism for Regulating Super-Enhancer Activity
… KRAS, and reduced the helicase activity of DDX55. Building on this framework, this study also identified a previously unrecognized role for polyP in transcriptional regulation through its direct interaction with components of the mammalian super-enhancer complex. PolyP modified the Mediator …
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Integrative analysis of transcriptomic data to elucidate regulators of pre-mRNA processing
… regulators of APA, most notably the RNA helicase DDX55, and provides the community with a standardized analysis resource for investigating APA regulation by RBPs. Finally, Chapter 6 introduces the Comparative Analysis of Alternative RNA Processing (CAARP), a lightweight framework and repository of …