Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"DDX5"”.
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Multiple Levels of Regulation of Cyclin-dependent Kinase Inhibitor 1A (p21/WAF-1) by the <i>DDX5 </i>Gene
… the p68 protein is not the only product of the DDX5 gene. DDX5 also gives rise to a long non-coding RNA species identified through retention of intron 11. Here I also present, through siRNA knockdown studies and analysis of the expression of the DDX5 lncRNA, p68 and p21 proteins in breast cancer …
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Investigating the function of DNA G-quadruplex structures in human enhancers
… II and one of its associated helicases DDX5 that is required for G4 function in enhancer activity. Overall, this thesis advances our understanding of G4s as functional elements of enhancers and provides mechanistic insight into how enhancers control the critical process of gene …
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Papel de la helicasa UAP56/DDX39B y otros factores asociados al metabolismo del ARN en la integridad del genoma
… de R loops tras el silenciamiento de UAP56 y DDX5 para investigar si ambas proteínas presentan una actividad redundante. Finalmente, hemos estudiado la contribución del factor de transcripción Snail1 a la integridad del genoma. Tradicionalmente, el estudio de esta proteína se ha enmarcado en …