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Showing 1 to 2 of 2 for “"DDX3Y"”.
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Regulation of human sex-linked homologs DDX3X and DDX3Y and phenotypic consequences
The X-linked gene DDX3X and its Y-linked homolog DDX3Y comprise one of 17 gene pairs retained on the human X and Y chromosomes during their evolution from ordinary autosomes; both genes are widely expressed in human tissues. Mutations of DDX3X and DDX3Y result in a wide range of sex-dependent …
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Elucidating the functions of RNA helicases DDX3X and DDX3Y in normal and malignant B cells
… for translation. Its Y chromosome paralogue, DDX3Y shares 92% amino acid conservation. DDX3X is ubiquitously expressed and considered pan essential. While DDX3Y is widely transcribed, its protein expression is predominantly limited to spermatogonia cells or at least restricted to very low …